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Epigenetics and Chromatin pp 1–30Cite as

Chromatin Remodeling Factors and DNA Replication

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Part of the book series: Progress in Molecular and Subcellular Biology ((PMSB,volume 38))

Abstract

Chromatin structures have to be precisely duplicated during DNA replication to maintain tissue-specific gene expression patterns and specialized domains, such as the centromeres. Chromatin remodeling factors are key components involved in this process and include histone chaperones, histone modifying enzymes and ATP-dependent chromatin remodeling complexes. Several of these factors interact directly with components of the replication machinery. Histone variants are also important to mark specific chromatin domains. Because chromatin remodeling factors render chromatin dynamic, they may also be involved in facilitating the DNA replication process through condensed chromatin domains.

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  1. Marie Curie Research Institute, The Chart, Oxted, Surrey, RH8 0TL, UK

    Patrick Varga-Weisz

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  1. Institute of Molecular Genetics of Montpellier, 1919 Route de Mende, 34293, Montpellier Cedex 05, France

    Philippe Jeanteur

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Varga-Weisz, P. (2005). Chromatin Remodeling Factors and DNA Replication. In: Jeanteur, P. (eds) Epigenetics and Chromatin. Progress in Molecular and Subcellular Biology, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27310-7_1

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