Abstract
Many problems, ranging from mild to severe, may arise postembolization that can be reduced or prevented if properly managed. During the early post-procedure period many patients may experience groin , buttock , and leg pains that may range from a minor hematoma , to pseudo aneurysm , to arterial obstruction resulting in thrombosis. Postembolization fever may be the result of either postembolization syndrome or bacterial infection. Generally prophylactic antibiotics are given to prevent bacterial infection and infection is generally associated with late onset fevers and increasing pain. The rate of hysterectomy following embolization is 3 %, possibly occurring as a result of unilateral embolization, collateral blood supply to the fibroids resulting in failure, or incomplete embolization. Patients who do not experience symptom relief, have extreme postembolization symptoms, or experience severe infections or septicemia may also undergo hysterectomy. Myomata that do undergo necrosis may be passed if small enough, or patients may receive a myomectomy to remove prolapsed myomata. Early onset of menopause post-UAE is more likely in women over 40, and extremely uncommon in those younger than 40. Success of UAE is considered relief of symptoms; however an MRI should be performed in the months following UAE to check for complications including leiomyomasarcoma and adenomyosis.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Agdi M, Valenti D, Tulandi T (2008) Intraabdominal adhesions after uterine artery embolization. Am J Obstet Gynecol 199:482.e1–482.e3. doi: 10.1016/j.ajog.2008.04.006
Al-Fozan H, Tulandi T (2002) Factors affecting early surgical intervention after uterine artery embolization. Obstet Gynecol Surv 57(12):810–815. doi:10.1097/00006254-200212000-00005
Brunereau L, Herbreteau D, Gallas S, Cottier J, Lebrun J, Tranquart F, Fauchier F, Body G, Rouleau P (2000) Uterine Artery Embolization in the Primary Treatment of Uterine Leiomyoma. AJR 175(5):1267–1272. doi: 10.2214/ajr.175.5.1751267
Czeyda-Pommersheim F, Magee ST, Cooper C, Hahn WY, Spies JB (2006) Venous thromboembolism after uterine fibroid embolization. J Cardio Interv Radiol 29:1136–1140. doi:10.1007/s00270-005-02453
Faro S, Saunders C, Aldridge K (1982) Use of single-agent antimicrobial therapy in the treatment of polymicrobial female pelvic infections. Obstet Gynecol 60(2):232–236. http://journals.lww.com/greenjournal/abstract/1982/08000/use_of_single_agent_antimicrobial_therapy_in_the.18.aspx Accessed Jan 8, 2012
Gabriel-Cox K, Jacobson GF, Armstrong MA, Hung YY (2007) Predictors of hysterectomy after uterine artery embolization for leiomyoma. Am J Obstet Gynecol 196:588.e1–588.e6. doi:10.1016/j.ajog.2007.03.014
Gall SA, Kohan AP, Ayers OM, Hughes CE, Addison AW, Hill GB (1981) Intravenous metronidazole or Clindamycin with Tobramycin for therapy of Pelvic infections. Obstet Gynecol 57(1):51–58. doi: 10.1016/S0140-6736(82)90503-7
Ghai S, Rajan DK, Benjamin MS, Asch MR (2005) Uterine artery embolization for leiomyomas: pre- and post-procedural evaluation with US. Radiogr 25:1159–1176. doi:10.1148/rg.255045019
Godfrey CD, Zbella EA (2001) Uterine necrosis after uterine artery embolization for leiomyoma. Obstet Gynecol 98:950–952. doi: 10.1016/S0029-7844(01)01483-1
Goldberg J, Boyle K, Choi M, Panchal N (2005) Small bowel obstruction due to adhesive disease observed after uterine myoma embolization. Am J Obstet Gynecol 193:892–893. doi:10.1016/j.ajog.2005.02.133
Goodwin SC, Reed RA (2000) Uterine artery embolization: an overview. Semin Intervent Radiol 17:237–246. doi:10.1055/s-2000-9411
Goodwin SC, Vedantham S, McLucas B, Forno AE, Parella R (1997) Preliminary experience with uterine artery embolization for uterine fibroids. J Vasc Interv Radiol 8(4):517–526. doi:10.1016/S1051-0443(97)70603-1
Goldman KN, Hirshfeld-Cytron JE, Pavone ME, Thomas AP, Vogelzang RL, Milad MP (2011) Uterine artery embolization immediately preceding laparoscopic myomectomy. Int J Gynaecol Obstet. doi:10.1016/j.ijgo.2011.08.022
Hamoda H, Tait P, Edmonds DK (2009) Fatal pulmonary embolus after uterine artery fibroid embolization. Cardiovascular Interventional Radiology 32(5):1080–1082. doi:10.1007/s00270-009-9589-4
Marret H, Cottier JP, Alonso AM, Giraudeau B, Body G, Herbreteau D (2004) Predictive factors for fibroids recurrence after uterine artery embolization. BJOG 112(4):461–465. doi: 10.1111/j.1471-0528.2004.00487.x
McDermott VG, Schuster MG, Smith TP (1997) Antibiotic prophylaxis in vascular and interventional radiology. Am J Roentgenol 169(1):31–38. doi: 10.2214/ajr.169.1.9207497
McLucas B (2008) Diagnosis, imaging, and classification of uterine fibroids. Clin Obstet Gynecol 22(4):627–642. doi:10.1016/j.bpobgyn.2008.01.006
McLucas B, Adler L, Perella R (2000) Uterine fibroid embolization: nonsurgical treatment for symptomatic fibroids. J Amer Coll of Surg 192:95–105. doi:10.1016/S1072-7515(00)00738-9
McLucas B, Chespak L, Kaminsky D (2008) Myoma necrosis following Gelfoam embolization of uterine myomata. J Min Invas Ther 17(3):200–204. doi:10.1080/13645700701627522
McLucas B, Goodwin S, Alder L (1998) Adhesion formation following embolization. Min Invas Ther Allied Technol 7:42
McLucas B, Goodwin SG, Lee M, Chen G, Perrella R, Muir S, Sayre J (1999) Uterine artery embolization for the treatment of uterine leiomyomata: midterm results. J Vasc Interv Radiol 10:1159–1165. doi:10.1016/S1051-0443(99)70213-7
McLucas B, Perrella R, Goodwin SG, Vedantham S, Forno A (1997) Preliminary experience with uterine artery embolization for uterine fibroids. J. Vasc Inter Rad 8(4):517. doi:10.1016/S1051-0443(97)70603-1
McLucas B, Perella R, Goodwin S, Adler L, Dalrymple J (2002) Role of uterine artery doppler flow in fibroid embolization. J Ultrasound Md 21:113–120. http://www.jultrasoundmed.org/content/21/2/113. Accessed 8 Jan 2012
Nott V, Reidy J F, Forman R G, Braudel (1999) Complications of fibroid embolisation. Min lnvas Ther Allied Techno 8(6): 426–424. doi: 10.3109/13645709909152917
Payne JF, Haney AF (2003) Serious complications of uterine artery embolization for conservative treatments of fibroids. Fertil Steril 79(1):128–131. doi:10.1016/S0015-0282(02)04398-4
Pelage JP, Dref OL, Soyer P, Kardache M, Dahan H, Abitbol M, Merland JJ, Ravina JH, Rymer R (2000) Fibroid-related menorrhagia treatment with selective embolization of the uterine arteries and midterm follow-up. J Radiol. http://radiology.rsna.org/content/215/2/428. Accessed 9 Sept 2011
Rajan DK, Beecroft JR, Timothy WI, Clark MSc, Asch MR, Simons ME, Kachura JR, Sved M, Sniderman KW (2004) Risk of intrauterine infectious complications after uterine artery embolization. J Vasc Interv Radio 15:1415–1421. doi: 10.1097/01.RVI.0000141337.52684.C4
Scheurig C, Gauruder-Burmester A, Kluner C, Kurzeja R, Lembcke A, Zimmermann E, Hamm B, Kroencke T (2006) Uterine artery embolization for symptomatic fibroids: short-term versus mid-term changes in disease-specific symptoms, quality of life and magnetic resonance imaging results. J Hum Repr 21(12):3270–3277. doi:10.1093/humrep/del275
Silverberg SG (1971) Leiomyosarcoma of the uterus. A clinicopathologic study. Obstet Gynecol 38:613–628. http://journals.lww.com/greenjournal/Abstract/1971/10000/LEIOMYOSARCOMA_OF_THE_UTERUS__A_Clinicopathologic.19.aspx. Accessed 1/8/2012
Slomka M, Radwan P (1992) The Evaluation of clinical results of hepatic artery embolization. Mater Med Pol 24:193-195. Accessed 1 Aug 2012
Smith SJ, Sewall LE, Handelsman A (1999) A clinical failure of uterine artery embolization due to adenomyosis. J Vasc Interv Radiol 10:1171–1174. doi:10.1016/S1051-0443(99)70216-2
Spies JB, Bruno J, Czeyda-Pommersheim F, Magee ST, Ascher SA, Jha RC (2005a) Long term outcome of uterine artery embolization of leiomyata. Obstet Gynecol 106(5):933–939. doi:10.1097/01.AOG.0000182582.64088.84
Spies JB, Myers ER, Worthington-Kirsch R, Mulgund J, Goodwin S, Mauro M (2005b) The fibroid registry: symptom and quality of life status 1 year after therapy. Obstet Gynecol 106(6):1309–1318. doi:10.1097/01.AOG.0000188386.53878.49
Spies JB, Spector A, Antionette R, Baker C, Chandra M, Mauro L, Murphy-Skrynarz K (2002) Complications after uterine artery embolization for leiomyomas. Obste Gynocol 100(5):873–880. doi:10.1016/S0029-7844(02)02341-4
Sweet RL (1981) Treatment of mixed aerobic-anaerobic infections of the female genital tract. J Antimicrob Chemother 8(D):105–114. doi: 10.1093/jac/8.suppl_D.105
Vashisht A, Studd J, Carey A et al (1999) Fetal septaecemia after myoma embolization. Lancet 354:307–308. doi:10.1016/S0140-6736(99)02987-6
Volkers NA, Hehenkamp WJK, Birnie E, de Vries C, Holt C, Ankum WM, Reekers JA (2006) Uterine artery embolization in the treatment of symptomatic uterine fibroid tumors (EMMY Trial): periprocedural results and complications. J Vasc Interv Rad 17(3):471–480. doi:10.1097/01.RVI.0000203419.61593.84
Walker W, Green A, Sutton C (1999) Bilateral uterine artery embolization for myomata: results, complications, and failures. Minim Invasive Ther Allied Technol 8(6):449–454. doi:10.3109/13645709909152923
Walker WJ, Pelage JP (2002) Uterine artery embolisation for symptomatic fibroids: clinical results in 400 women with imaging follow up. BJOG: Intern J Obst Gyn 109:1262–1272 doi:10.1046/j.1471-0528.2002.01449.x
Weed HG (2003) Antimicrobial prophylaxis in the surgical patient. Med Clin N Am 87:59–75. doi:10.1016/S0025-7125(02)00145-1
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer Berlin Heidelberg
About this chapter
Cite this chapter
McLucas, B. (2014). Postembolization Problems and Management. In: Reidy, J., Hacking, N., McLucas, B. (eds) Radiological Interventions in Obstetrics and Gynaecology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2014_973
Download citation
DOI: https://doi.org/10.1007/174_2014_973
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-27974-4
Online ISBN: 978-3-642-27975-1
eBook Packages: MedicineMedicine (R0)