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Focal Therapy and the Index Lesion Hypothesis in Prostate Cancer

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Book cover Radiotherapy in Prostate Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Standard whole gland radiation therapy for prostate cancer results in high cure rates but impacts quality of life. Active surveillance is an alternative but has not been widely embraced. Focal therapy represents a middle ground between these two treatment options. In this paper we will review the rationale, patient selection considerations, technical planning issues, and recent clinical data for prostate focal therapy.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, University of California Los Angeles, 200 UCLA Medical Plaza, Suite B265, Los Angeles, CA, 90095, US

    Mitchell Kamrava & Patrick Kupelian

Authors
  1. Mitchell Kamrava
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  2. Patrick Kupelian
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Corresponding author

Correspondence to Mitchell Kamrava .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, Krankenhaus der Barmherzigen, Schwestern Linz, Johannes Kepler University, Linz, Austria

    Hans Geinitz

  2. University of California, San Francisco Department of Radiation Oncology, San Francisco, California, USA

    Mack Roach III

  3. The Institute of Cancer Research Sutton, Sutton Surrey, United Kingdom

    Nicholas van As

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© 2013 Springer-Verlag Berlin Heidelberg

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Kamrava, M., Kupelian, P. (2013). Focal Therapy and the Index Lesion Hypothesis in Prostate Cancer. In: Geinitz, H., Roach III, M., van As, N. (eds) Radiotherapy in Prostate Cancer. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2013_913

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  • DOI: https://doi.org/10.1007/174_2013_913

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-37098-4

  • Online ISBN: 978-3-642-37099-1

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