Skip to main content

The Aetiology of Vascular Disease

  • Chapter
Vascular Interventional Radiology

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 2375 Accesses

Abstract

This chapter explains how and why vascular disease processes evolve into the lesions encountered by interventional radiologists.  

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Anderson TJ (1999) Assessment and treatment of endothelial dysfunction in humans. J Am Coll Cardiol 34:631–638

    Article  PubMed  CAS  Google Scholar 

  • Arunodaya GR, Vani S, Shankar SK et al (1997) Fibromuscular dysplasia with dissection of basilar artery presenting as “locked-in-syndrome”. Neurology 48:1605–1608

    Article  PubMed  CAS  Google Scholar 

  • Begelman SM, Olin JW (2000) Fibromuscular dysplasia. Curr Opin Rheumatol 12:41–47

    Article  PubMed  CAS  Google Scholar 

  • Bengtsson H, Bergqvist D, Sternby NH (1992) Increasing prevalence of abdominal aortic aneurysms: A necropsy study. Eur J Surg 158:19–23

    PubMed  CAS  Google Scholar 

  • Brady AR, Fowkes FG, Thompsom SG et al (2001) Aortic aneurysm diameter and risk of cardiovascular mortality. Arterioscler Thromb Vasc Biol 21:1203–1207

    Article  PubMed  CAS  Google Scholar 

  • Campa JS, Greenhalah RM, Powell JT (1987) Elastin degredation in abdominal aortic aneurysms. Atherosclerosis 65:13–21

    Article  PubMed  CAS  Google Scholar 

  • Cloft HJ, Kallmes DF, Kallmes MH et al (1998) Prevalence of cerebral aneurysms in patients with fibromuscular dysplasia: a reassessment. J Neurosurg 88:436–440

    Article  PubMed  CAS  Google Scholar 

  • Cohen JR, Keegan L, Sarfati I et al (1991) Neutrophil chemotaxis and neutrophil elastase in the aortic wall in those patients with abdominal aortic aneurysms. J Invest Surg 4:423–430

    Article  PubMed  CAS  Google Scholar 

  • Davis MJ, Richardson PD, Woolf N et al (1993) Risk of thrombosis in human atherosclerotic plaques: role of extracellular lipid, macrophage and smooth muscle cell content. Br Heart J 69:3777–3781

    Google Scholar 

  • Eachempati SR, Sebastian MW, Reed RL 2nd (1998) Posttraumatic bilateral carotid artery and right vertebral artery dissections in a patient with fibromuscular dysplasia: case report and review of the literature. J Trauma 44:406–409

    Article  PubMed  CAS  Google Scholar 

  • Fowkes FG, Housley E, Riemersama RA et al (1992) Smoking, lipids, glucose intolerance, and blood pressure as risk factors for peripheral atherosclerosis compared with ischaemic heart disease in the Edinburgh Artery Study. Am J Epidemiol 135:331–340

    PubMed  CAS  Google Scholar 

  • Furchgott RF, Zawadski JV (1980) The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288:373–376

    Article  PubMed  CAS  Google Scholar 

  • Zs Galis, Khatri JJ (2002) Matrix metalloproteinases in vascular remodelling and atherogenisis: the good, the bad and the ugly. Circ Res 90:251–262

    Google Scholar 

  • Gaziano JM (1996) Epidemiology of risk-factor reduction. In: Loscalzo J, Creager MA, Dzau VJ (eds) Vascular Medicine. Little Brown, Boston, p 569

    Google Scholar 

  • Glagov S, Weisenburg E, Zairns CK et al (1987) Compensatory enlargement of human atherosclerotic coronary arteries. N Eng J Med 316:1371–1375

    Article  CAS  Google Scholar 

  • Gray GH, Young JR, Olin JW (1996) Miscellaneous arterial diseases. In: Young JR, Olin JW, Bartholomew J (eds) Peripheral vascular diseases, 2nd edn. Mosby-Yearbook, St Louis, pp 425–440

    Google Scholar 

  • Haffner SM, Alexander CM, Cook TJ et al (1999) Reduced coronary events in simvastatin-treated patients with coronary heart disease and diabetes or impaired fasting glucose levels: subgroup analyses in the Scandinavian Simvastatin Survival Study. Arch Intern Med 159:2661–2667

    Article  PubMed  CAS  Google Scholar 

  • Hagan PG, Nienaber CA, Issenbacher EM et al (2000) International registry of acute aortic dissection (IRAD) New insight into an old disease. JAMA 283:897

    Article  PubMed  CAS  Google Scholar 

  • Hansson G (2001) Immune mechanisms in atherosclerosis. Atheroscler Thromb Vasc Biol 21:1876–1890

    Article  CAS  Google Scholar 

  • Harrison EG Jr, McCormack LJ (1971) Pathologic classification of renal arterial disease in renovascular hypertension. Mayo Clin Proc 46:161–167

    PubMed  Google Scholar 

  • Hill LD, Antonius JI (1965) Arterial dysplasia: an important surgical lesion. Arch Surg 90:585–595

    Article  PubMed  CAS  Google Scholar 

  • Hirose H, Takagi M, Miyagawa N (1998) Genetic risk factor for abdominal aortic aneurysm: HLA-DR2(15), a Japanese study. J Vasc Surg 27:500–503

    Article  PubMed  CAS  Google Scholar 

  • Johnson JR, Leger W, Lucas CE (1993) Mycotic aneurysm, new concepts in therapy. Arch Surg 118:577

    Article  Google Scholar 

  • Kannel WB, McGee DL (1985) Update on some epidemiologic features of intermittent claudication: the Framingham study. J Am Geriat Soc 33:13–18

    PubMed  CAS  Google Scholar 

  • Leadbetter WF, Burkland CD (1938) Hypertension in unilateral renal disease. J Urol 39:611–626

    Google Scholar 

  • Libby P (2000) Changing concepts of atherogenesis. J Intern Med 247:349–358

    Article  PubMed  CAS  Google Scholar 

  • Libby P (2002) Inflammation in atherosclerosis. Nature 420:868–874

    Article  PubMed  CAS  Google Scholar 

  • Loscalzo J (2001) Nitrous oxide insufficiency, platelet activation and arterial thrombosis. Circ Res 88:756–762

    Article  PubMed  CAS  Google Scholar 

  • Ludmer PL, Selwyn AP, Shook TL et al (1986) Paradoxial vasoconstrictiuon induced by acetylcholine in coronary arteries. N Engl J Med 315:1046–1051

    Article  PubMed  CAS  Google Scholar 

  • Luscher TF, Lie JT, Stanson AW et al (1987) Arterial fibromuscular dysplasia. Mayo Clin Proc 62:931–952

    PubMed  CAS  Google Scholar 

  • Makin A, Silverman SH, Lip GY (2002) Peripheral vascular disease and Virchow’s triad for thrombogenisis. QJM 95:199–210

    Article  PubMed  CAS  Google Scholar 

  • Messina LM, Brothers TE, Wakefield TW, Zelenock GB, Lindenauer SM, Greenfield LJ, Jacobs LA, Fellows EP, Grube SV, Stanley JC (1991) Clinical characteristics and surgical management of vascular complications in patients undergoing cardiac catheterization: interventional versus diagnostic procedures. J Vasc Surg 13:593–600

    Article  PubMed  CAS  Google Scholar 

  • MacFarlane RG (1964) An enzyme cascade in the blood clotting mechanism and its function as a biochemical amplifier. Nature 207(4931):498–499

    Article  Google Scholar 

  • Meszaros I, Morocz J, Szlavi J (2000) Epidemiology and clinopathology of aortic dissection. A Population based longitudinal study over 27 years. Chest 117:1271

    Article  PubMed  CAS  Google Scholar 

  • McCormack LJ, Poutasse EF, Meaney TF et al (1966) A pathologic-arteriographic correlation of renal arterial disease. Am Heart J 72:188–198

    Article  PubMed  CAS  Google Scholar 

  • Pannier-Moreau I, Grimbert P, Fiquet-Kempf B et al (1997) Possible familial origin of multifocal renal artery fibromuscular dysplasia. J Hypertens 15:1797–1801

    Article  PubMed  CAS  Google Scholar 

  • Pastercamp G, de Kleijn DP, Borst C (2000) Arterial remodelling in atheroscleroisis, restenosis and after alteration of blood flow: potential mechanisms and clinical implications. Cardiovasc Res 45:843–852

    Article  Google Scholar 

  • Quick CR, Cotton LT (1982) The measured effect of stopping smoking on intermittent claudication. Br J Surg 699 (Suppl):S24–S26

    Article  Google Scholar 

  • Raines EW (2000) The extracellular matrix can regulate vascular cell migration, proliferation and survival: relationships to vascular disease. Int J Exp Pathol 81:173–182

    Article  PubMed  CAS  Google Scholar 

  • Rasmussen TE, Hallett JW Jr (1997) Inflammatory aortic aneurysms. A clinical review with new perspectives in pathogenesis. Ann Surg 225:155–164

    Article  PubMed  CAS  Google Scholar 

  • Rauch U, Osende JI, Fuster V et al (2001) Thrombosis formation on atherosclerotic plaques: pathogenisis and clinical consequences. Ann Intern Med 134:2224–2238

    Google Scholar 

  • Rehm JP, Grange JJ, Baxter BT (1998) The formation of aneurysms. Semin Vasc Surg 11(3):193–202

    Google Scholar 

  • Rekhter MD (1999) Collagen synthesis in atherosclerosis too much and not enough. Cardiovasc Res 41:376–384

    Article  PubMed  CAS  Google Scholar 

  • Richter GM, Palmez, JC, Noedge G et al (2000) Blood flow and thrombus formation in the development of stent neo intima. J Long Term Eff Med Implants 10(1–2):67–77

    Google Scholar 

  • Rivard A, Andres V (2000) Vascular smooth muscle cell proliferation in the pathogenisis of atherosclerotic cardiovascular diseases. Histol Histopathol 15:557–571

    PubMed  CAS  Google Scholar 

  • Rosenfeld ME (1996) Cellular mechanisms in the development of atherosclerosis. Diabetes Res Clin Pract 30(Suppl):1–11

    Article  PubMed  Google Scholar 

  • Salo JA, Soisalon-Soininen S, Bondestam S (1999) Familial occurrence of abdominal aortic aneurysm. Ann Intern Med 130:637–642

    PubMed  CAS  Google Scholar 

  • Schievink WI, Limburg M (1989) Angiographic abnormalities mimicking fibromuscular dysplasia in a patient with Ehlers-Danlos syndrome, type IV. Neurosurgery 25:482–483

    Article  PubMed  CAS  Google Scholar 

  • Schievink WI, Meyer FB, Parisi JE et al (1998) Fibromuscular dysplasia of the internal carotid artery associated with alpha1-antitrypsin deficiency. Neurosurgery 43:229–233

    Article  PubMed  CAS  Google Scholar 

  • Schonbeck U, Libby P (2001) CD40 signalling and plaque instability. Circ Res 89:1092–1103

    Article  PubMed  CAS  Google Scholar 

  • Somers P, Knaapen M (2006) The histopathology of varicose vein disease. Angiology 57(5):546

    Article  PubMed  Google Scholar 

  • Tilson MD (1988) Histochemistry of aortic elastin in patients with non-specific abdominal aortic aneurysm disease. Arch Surg 123:503–505

    Article  PubMed  CAS  Google Scholar 

  • Topper JN, Gimbrone MA Jr (1999) Blood flow and vascular gene expression: fluid shear stress as a modulator of endothelial phenotype. Mol Med Today 5:40–46

    Article  PubMed  CAS  Google Scholar 

  • Tromp G, Wu Y, Prockop DJ et al (1993) Sequencing of cDNA from 50 unrelated patients reveals that mutations in the triple-helical domain of type III procollagen are an infrequent cause of aortic aneurysms. J Clin Invest 91:2539–2545

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to R. D. Wells .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Wells, R.D. (2012). The Aetiology of Vascular Disease. In: Cowling, M. (eds) Vascular Interventional Radiology. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2012_552

Download citation

  • DOI: https://doi.org/10.1007/174_2012_552

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-27877-8

  • Online ISBN: 978-3-642-27878-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics