Abstract
Glioneuronal rather than glial tumors are found in around 20% of patients with drug-resistant focal epilepsies. Gangliogliomas, dysembryoplastic neuroepithelial tumours (DNTs), angiocentric gliomas, pilocytic astrocytomas, and pleomorphic xanthoastrocytomas (PXAs) show characteristic imaging profiles clearly different from diffusely infiltrating gliomas. Epidermoids and dermoids are considered tumor like lesions with likewise specific imaging findings.
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References
Bien CG, Raabe AL, Schramm J, Becker AJ, Urbach H, Elger CE (2013) Trends in presurgical evaluation and surgical treatment of epilepsy at one centre from 1988 to 2009. J Neurol Neurosurg Psychiatry, Jan 84(1):54–61. doi:10.1136/jnnp-2011-301763
Blümcke I, Wiestler OD (2002) Gangliogliomas: an intriguing tumor entity associated with focal epilepsies. J Neuropathol Exp Neurol 61:575–584
Blümcke I, Giencke K, Wardelmann E et al (1999) The CD34 epitope is expressed in neoplastic and malformative lesions associated with chronic, focal epilepsies. Acta Neuropathol 97:481–490
Campos AR, Clusmann H, von Lehe M, Niehusmann P, Becker AJ, Schramm J, Urbach H (2009) Simple and complex dysembryoplastic neuroepithelial tumors (DNT): clinical profile MRI and histopathology. Neuroradiology 51:433–443
Daumas-Duport C, Scheithauer BW, Chodkiewicz JP, Laws ER Jr, Vedrenne C (1988) Dysembryoplastic neuroepithelial tumor: a surgically curable tumor of young patients with intractable partial seizures. Report of 39 cases. Neurosurgery 23:545–556
Daumas-Duport C, Pietsch T, Lantos PL (2000) Dysembryoplastic neuroepithelial tumour. In: Kleihues P, Cavenee K (eds) Pathology and genetic of tumours of the nervous system. IARC press, Lyon
Lellouch-Tubiana A, Boddaert N, Bourgeois M, Fohlen M, Jouvet A, Delalande O, Seidenwurm D, Brunelle F, Saint-Rose C (2005) Angiocentric neuroepithelial tumor (ANET): a new Epilepsy-related clinicopathological entity with distinctive MRI. Brain Pathol 15:281–286
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114:97–109
Luyken C, Blümcke I, Fimmers R, Urbach H, Wiestler OD, Schramm J (2003) The spectrum of long-term epilepsy associated tumors: long-term seizure and tumor outcome and neurosurgical aspects. Epilepsia 44:822–830
Luyken C, Blümcke I, Fimmers R, Urbach H, Wiestler OD, Schramm J (2004) Supratentorial gangliogliomas. Histopathological grading and tumor recurrence in 184 patients with a median follow-up of eight years. Cancer 101:146–155
Majores M, Niehusmann P, von Lehe M, Blümcke I, Urbach H (2007) Angiocentric neuroepithelial tumour mimicking Ammon’s horn sclerosis. Clin Neuropathol 26:311–316
Majores M, von Lehe M, Fassunke J, Schramm J, Becker AJ, Simon M (2008) Tumor recurrence and malignant progression of gangliogliomas. Cancer 113:3355–3363
Okamoto Y, Di Patre PL, Burkhard C, Horstmann S, Jourde B, Fahey M, Schüler D, Probst-Hensch NM, Yasargil MG, Yonekawa Y, Lütolf UM, Kleihues P, Ohgaki H (2004) Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas. Acta Neuropathol 108(1):49–56
Perkins OC (1926) Gangliogliomas. Arch Pathol Lab Med 2:11–17
Provenzale JM, Ali U, Barboriak DP, Kallmes DF, Delong DM, McLendon RE (2000) Comparison of patient age with MR imaging features of gangliogliomas. Am J Roentgenol 174:859–862
Rumana CS, Valadka AB, Contant CF (1999) Prognostic factors in supratentorial ganglioglioma. Acta Neurochir (Wien) 141:63–69
Shakur SF, McGirt MJ, Johnson MW, Burger PC, Ahn E, Carson BS, Jallo GI (2009) Angiocentric glioma: a case series. J Neurosurg Pediatr 3:197–202
Wang M, Tijan T, Rojiani AM, Bodhireddy SR, Prayson RA, Iacuone JJ, Alles AJ, Donahue DJ, Hessler RB, Kim JH, Haas M, Rosenblum MK, Burger PC (2005) Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma. J Neuropathol Exp Neurol 64:875–881
Zentner J, Wolf HK, Ostertun B, Hufnagel A, Campos MG, Solymosi L, Schramm J (1994) Gangliogliomas: clinical, radiological and histopathological findings in 51 patients. J Neurol Neurosurg Psychiatry 57:1497–1502
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Urbach, H. (2013). Epilepsy Associated Tumors And Tumor-Like Lesions. In: Urbach, H. (eds) MRI in Epilepsy. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_525
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DOI: https://doi.org/10.1007/174_2011_525
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