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Systemic Vasculitis pp 15–23Cite as

Systemic Vasculitis: Anatomy and Histopathology

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Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Vasculitides are defined by inflammation of the blood vessel walls leading to vascular stenosis or occlusion, with various degrees of fibrinoid necrosis of the media and inflammatory infiltration, mainly neutrophilic and sometimes granulomatous. Systemic vasculitides are classified according to their clinical presentations, their precise histological features, and the size of the predominantly affected vessels. Some of them are necrotizing: there is fibrinoid necrosis of the media with endothelial inflammatory infiltration and an inflammatory reaction of the adventitia frequently associated with lumen thrombosis. Others are non-necrotizing, and show giant cell infiltration and destruction of the internal elastic lamina. Finally, there are leucocytoclasic vasculitides without giant cell infiltrate or fibrinoid necrosis.

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Author information

Authors and Affiliations

  1. Medical School of Tunis, Department of Pathology, Mongi Slim University Hospital, La Marsa, 2046, Sidi Daoud, Tunisia

    Ahlem Lahmar & Sabeh Mzabi-Regaya

  2. Medical School of Tunis, Department of Pathology, La Rabta University Hospital, 1007, Tunis, Tunisia

    Samir Boubaker

  3. Medical School of Tunis, Department of Anatomo-pathology, La Rabta University Hospital, 1007, Tunis, Tunisia

    Nidhameddine Kchir

  4. Medical School of Tunis, Department of Medical Imaging and Imaging Guided Interventions, Mongi Slim University Hospital, La Marsa, 2046, Sidi Daoud, Tunisia

    Lotfi Hendaoui

Authors
  1. Ahlem Lahmar
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  2. Sabeh Mzabi-Regaya
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  3. Samir Boubaker
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  4. Nidhameddine Kchir
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  5. Lotfi Hendaoui
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Corresponding author

Correspondence to Ahlem Lahmar .

Editor information

Editors and Affiliations

  1. Medical School of Tunis, Department of Medical Imaging, Hôpital Mongi Slim, La Marsa, 2046, Tunisia

    Lotfi Hendaoui

  2. Mayo Graduate School of Medicine, Gonda Vascular Center, Mayo Clinic, Rochester, 55902, Minnesota, USA

    Anthony W. Stanson

  3. Medical School of Tunis, Department of Medical Imaging, Interior Security Forces Teaching Hospit, La Marsa, 2070, Tunisia

    M. Habib Bouhaouala

  4. Medical School of Toulouse University, Department of Medical Imaging, Rangueil Hospital, Toulouse CX 9, 31059, France

    Francis Joffre

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© 2011 Springer-Verlag Berlin Heidelberg

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Lahmar, A., Mzabi-Regaya, S., Boubaker, S., Kchir, N., Hendaoui, L. (2011). Systemic Vasculitis: Anatomy and Histopathology. In: Hendaoui, L., Stanson, A., Bouhaouala, M., Joffre, F. (eds) Systemic Vasculitis. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_234

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  • DOI: https://doi.org/10.1007/174_2011_234

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-02483-2

  • Online ISBN: 978-3-642-02484-9

  • eBook Packages: MedicineMedicine (R0)

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