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Nonischemic Colitis

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CT of the Acute Abdomen

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

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Abstract

Many patients with acute colitis present with abdominal pain or other nonspecific symptoms. In these patients, multidetector row CT is often used as the initial diagnostic test, which plays a pivotal role. This imaging technique can demonstrate inflammatory changes in the colonic wall, determine the extent of the disease, and detect the potential complications. In addition, multidetector row CT helps identify myriad extracolonic conditions that are responsible for the nonspecific symptoms should the patients have a cause of symptoms other than colitis. In most cases, the specific cause of colitis is determined on the basis of the results of clinical examination, laboratory tests, optical colonoscopy, and colonic biopsy. However, in equivocal cases or emergency situations, multidetector row CT findings help narrow the differential diagnosis. Many multidetector row CT features or patterns are helpful in distinguishing between the various types of colitis. They include the degree of wall thickening and colonic edema, the extent and location of the disease, extraluminal manifestations, and types of complication. Multidetector row CT has a critical role in determining the most appropriate therapeutic approach in a substantial number of cases.

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References

  • Adams GW, Rauch RF, Kelvin FM, Silverman PM, Korobkin M (1985) CT detection of typhlitis. J Comput Assist Tomogr 9:363–365

    Article  PubMed  CAS  Google Scholar 

  • Balthazar EJ (1991) CT of the gastrointestinal tract: principles and interpretation. AJR Am J Roentgenol 156:23–32

    PubMed  CAS  Google Scholar 

  • Boudiaf M, Zidi SH, Soyer P, Lavergne-Slove A, Kardache M, Logeay O, Rymer R (1998) Tuberculous colitis mimicking Crohn’s disease: utility of computed tomography in the differentiation. Eur Radiol 8:1221–1223

    Article  PubMed  CAS  Google Scholar 

  • Boudiaf M, Soyer P, Pelage JP, Kardache M, Nemeth J, Dufresne AC, Rymer R (2000) CT of radiation-induced injury of the gastrointestinal tract: spectrum of findings with barium studies correlation. Eur Radiol 10:920–925

    Article  PubMed  CAS  Google Scholar 

  • Bradley SJ, Weaver DW, Maxwell NP, Bouwman DL (1988) Surgical management of pseudomembranous colitis. Am Surg 54:329–332

    PubMed  CAS  Google Scholar 

  • Cao J, Liu WJ, Xu XY, Zou XP (2010) Endoscopic findings and clinicopathologic characteristics of colonic schistosomiasis: a report of 46 cases. World J Gastroenterol 16:723–727

    Article  PubMed  Google Scholar 

  • Casola G, vanSonnenberg E, Neff CC, Saba RM, Withers C, Emarine CW et al (1987) Abscesses in Crohn disease: percutaneous drainage. Radiology 163:19–22

    PubMed  CAS  Google Scholar 

  • Choi D, Jin Lee S, Ah Cho Y et al (2003) Bowel wall thickening in patients with Crohn’s disease: CT patterns and correlation with inflammatory activity. Clin Radiol 58:68–74

    Article  PubMed  Google Scholar 

  • Connor R, Jones B, Fishman EK, Siegelman SS (1984) Pneumatosis intestinalis: role of computed tomography in diagnosis and management. J Comput Assist Tomogr 8:269–275

    PubMed  CAS  Google Scholar 

  • Da Ines D, Petitcolin V, Lannareix W, Essamet W, Tournilhac O, Garcier JM (2010) CT imaging features of colitis in neutropenic patients. J Radiol 91:675–686

    Article  PubMed  CAS  Google Scholar 

  • Fishman EK, Wolf EJ, Jones B, Bayless TM, Siegelman SS (1987) CT evaluation of Crohn’s disease: effect on patient management. AJR Am J Roentgenol 148:537–540

    PubMed  CAS  Google Scholar 

  • Fishman EK, Kavuru M, Jones B (1991) Pseudomembranous colitis: CT evaluation of 26 cases. Radiology 180:57–60

    PubMed  CAS  Google Scholar 

  • Frager DH, Goldman M, Beneventano TC (1983) Computed tomography in Crohn disease. J Comput Assist Tomogr 7:819–824

    Article  PubMed  CAS  Google Scholar 

  • Frager DH, Frager JD, Wolf EL, Rand LG, St Onge G, Mitsudo S, Bodner L, Brandt LJ, Beneventano TC (1986) Cytomegalovirus colitis in acquired immune deficiency syndrome: radiologic spectrum. Gastrointest Radiol 11:241–246

    Article  PubMed  CAS  Google Scholar 

  • Frick MP, Maile CW, Crass JR, Goldberg ME, Delaney JP (1984) Computed tomography of neutropenic colitis. AJR Am J Roentgenol 143:763–765

    PubMed  CAS  Google Scholar 

  • Frommhold W, Hubener KH (1981) The role of computerized tomography in the after care of patients suffering from carcinoma of the rectum. J Comput Assist Tomogr 5:161–168

    Article  CAS  Google Scholar 

  • Funayama Y, Sasaki I, Naito H et al (1996) Psoas abscess complicating Crohn’s disease: report of two cases. Surg Today 26:345–348

    Article  PubMed  CAS  Google Scholar 

  • Furukawa A, Saotome T, Yamasaki M et al (2004) Cross-sectional imaging in Crohn disease. Radiographics 24:689–702

    Article  PubMed  Google Scholar 

  • Gayer G, Apter S, Zissin R (2002) Typhlitis as a rare cause of a psoas abscess. Abdom Imaging 27:600–602

    Article  PubMed  CAS  Google Scholar 

  • Gilinsky NH, Burns DG, Barbezat GO, Levin W, Myers HS, Marks IN (1983) The natural history of radiation-induced proctosigmoiditis: an analysis of 88 patients. Q J Med 52:40–53

    PubMed  CAS  Google Scholar 

  • Gomez L, Martino R, Rolston KV (1998) Neutropenic enterocolitis: spectrum of the disease and comparison of definite and possible cases. Clin Infest Dis 27:695–699

    Article  CAS  Google Scholar 

  • Gore RM, Marn CS, Kirby DF, Vogelzang RL, Neiman HL (1984) CT findings in ulcerative, granulomatous, and indeterminate colitis. AJR Am J Roentgenol 143:279–284

    PubMed  CAS  Google Scholar 

  • Gore RM, Balthazar EJ, Ghahremani GG, Miller FH (1996) CT features of ulcerative colitis and Crohn’s disease. AJR Am J Roentgenol 167:3–15

    PubMed  CAS  Google Scholar 

  • Gossios KJ, Tsianos EV (1997) Crohn disease: CT findings after treatment. Abdom Imaging 22:160–163

    Article  PubMed  CAS  Google Scholar 

  • Herlinger H, Furth EE, Rubesin SE (1998) Fibrofatty proliferation of the mesentery in Crohn disease. Abdom Imaging 23:446–468

    Article  PubMed  CAS  Google Scholar 

  • Hoeffel C, Crema MD, Belkacem A, Azizi L, Lewin M, Arrivé L, Tubiana JM (2006) Multi-detector row CT: spectrum of diseases involving the ileocecal area. Radiographics 26:1373–1790

    Article  PubMed  Google Scholar 

  • Horton KM, Corl FM, Fishman EK (2000) CT evaluation of the colon: inflammatory disease. Radiographics 20:399–418

    PubMed  CAS  Google Scholar 

  • Imbriaco M, Balthazar EJ (2001) Toxic megacolon: role of CT in evaluation and detection of complications. Clin Imaging 25:349–354

    Article  PubMed  CAS  Google Scholar 

  • Jafri SF, Marshall LB (1996) Ascites associated with antibiotic-associated pseudomembranous colitis. South Med J 89:1014–1017

    Article  PubMed  CAS  Google Scholar 

  • Jobe BA, Grasley A, Deveney KE, Deveney CW, Sheppard BC (1995) Clostridium difficile colitis: an increasing hospital-acquired illness. Am J Surg 169:480–483

    Article  PubMed  CAS  Google Scholar 

  • Jones B, Fishman EK, Hamilton SR et al (1986a) Submucosal accumulation of fat in inflammatory bowel disease: CT/pathologic correlation. J Comput Assist Tomogr 10:759–763

    Article  PubMed  CAS  Google Scholar 

  • Jones B, Fishman EK, Kramer SS (1986b) Computed tomography of gastrointestinal inflammation after bone marrow transplantation. AJR Am J Roentgenol 146:691–695

    PubMed  CAS  Google Scholar 

  • Kalantari BN, Mortelé KJ, Cantisani V (2003) CT features with pathologic correlation of acute gastrointestinal graft-versus-host disease after bone marrow transplantation in adults. AJR Am J Roentgenol 181:1621–1625

    PubMed  Google Scholar 

  • Kalra MK, Maher MM, Toth TL, Schmidt B, Westerman BL, Morgan HT et al (2004) Techniques and applications of automatic tube current modulation for CT. Radiology 233:649–657

    Article  PubMed  Google Scholar 

  • Kawamoto S, Horton KM, Fishman EK (1999) Pseudomembranous colitis: can CT predict which patients will need surgical intervention? J Comput Assist Tomogr 23:79–85

    Article  PubMed  CAS  Google Scholar 

  • Kelly CP, Pothoulakis C, LaMont JT (1994) Clostridium difficile colitis. N Engl J Med 330:257–262

    Article  PubMed  CAS  Google Scholar 

  • Kimose HH, Fischer L, Spjeldmaes N, Wara P (1989) Late radiation injury of the colon and rectum: surgical management and outcome. Dis Colon Rectum 32:684–689

    Article  PubMed  CAS  Google Scholar 

  • Kirkpatrick ID, Greenberg HM (2001) Evaluating the CT diagnosis of Clostridium difficile colitis: should CT guide therapy? AJR Am J Roentgenol 176:635–639

    PubMed  CAS  Google Scholar 

  • Kirkpatrick ID, Greenberg HM (2003) Gastrointestinal complications in the neutropenic patient: characterization and differentiation with abdominal CT. Radiology 226:668–674

    Article  PubMed  Google Scholar 

  • Klingler PJ, Metzger PP, Seelig MH, Pettit PD, Knudsen JM, Alvarez SA (2000) Clostridium difficile infection: risk factors, medical and surgical management. Dig Dis 18:147–160

    Article  PubMed  CAS  Google Scholar 

  • Kralovich KA, Sacksner J, Karmy-Jones RA, Eggenberger JC (1997) Pseudomembranous colitis with associated fulminant ileitis in the defunctionalized limb of a jejunalileal bypass: report of a case. Dis Colon Rectum 40:622–624

    Article  PubMed  CAS  Google Scholar 

  • Kuehne SA, Cartman ST, Heap JT, Kelly ML, Cockayne A, Minton NP (2010) The role of toxin A and toxin B in Clostridium difficile infection. Nature 467:711–773

    Google Scholar 

  • Latella G, Vernia P, Viscido A et al (2002) GI distension in severe ulcerative colitis. Am J Gastroenterol 97:1169–1175

    Article  PubMed  Google Scholar 

  • Lee SS, Ha HK, Yang SK et al (2002) CT of prominent pericolic or perienteric vasculature in patients with Crohn’s disease: correlation with clinical disease activity and findings on barium studies. AJR Am J Roentgenol 179:1029–1036

    PubMed  Google Scholar 

  • Lefèvre A, Soyer P, Vahedi K, Guerrache Y, Bellucci S, Gault V, Boudiaf M (2011) Multiple intra-abdominal venous thrombosis in ulcerative colitis: role of MDCT for detection. Clin Imaging 35:68–72

    Google Scholar 

  • Ma LD, Jones B, Lazenby AJ, Douglas T, Bulte JW (1994) Persistent oral contrast agent lining the intestine in severe mucosal disease: elucidation of radiographic appearance. Radiology 191:747–749

    PubMed  CAS  Google Scholar 

  • Macari M, Balthazar EJ (2001) CT of bowel wall thickening: significance and pitfalls of interpretation. AJR Am J Roentgenol 176:1105–1116

    PubMed  CAS  Google Scholar 

  • Macari M, Balthazar EJ, Megibow AJ (1999) The accordion sign at CT: a nonspecific finding in patients with colonic edema. Radiology 211:743–746

    PubMed  CAS  Google Scholar 

  • Makanjuola D (1998) Is it Crohn’s disease or intestinal tuberculosis? CT analysis. Eur J Radiol 28:55–61

    Article  PubMed  CAS  Google Scholar 

  • McDonald JB, Middleton PJ (1976) Tuberculosis of the colon simulating carcinoma. Radiology 118:293–294

    PubMed  CAS  Google Scholar 

  • Merine D, Fishman EK, Jones B (1987a) Pseudomembranous colitis: CT evaluation. J Comput Assist Tomogr 11:1017–1020

    Article  PubMed  CAS  Google Scholar 

  • Merine DS, Fishman EK, Jones B, Nussbaum AR, Simmons T (1987b) Right lower quadrant pain in the immunocompromised patient: CT findings in 10 cases. AJR Am J Roentgenol 149:1177–1179

    PubMed  CAS  Google Scholar 

  • Moir CR, Scudamore CH, Benny WB (1986) Typhlitis: selective surgical management. Am J Surg 151:563–566

    Article  PubMed  CAS  Google Scholar 

  • Morris JB, Zollinger RM Jr, Stellato TA (1990) Role of surgery in antibiotic-induced pseudomembranous enterocolitis. Am J Surg 160:535–539

    Article  PubMed  CAS  Google Scholar 

  • Otaibi AA, Barker C, Anderson R, Sigalet DL (2002) Neutropenic enterocolitis (typhlitis) after pediatric bone marrow transplant. J Pediatr Surg 37:770–772

    Article  PubMed  Google Scholar 

  • Otchy DP, Nelson H (1993) Radiation injuries of the colon and rectum. Surg Clin North Am 73:1017–1035

    PubMed  CAS  Google Scholar 

  • Papa A, Scaldaferri F, Danese S, Guglielmo S, Roberto I, Bonizzi M, Mocci G, Felice C, Ricci C, Andrisani G, Fedeli G, Gasbarrini G, Gasbarrini A (2008) Vascular involvement in inflammatory bowel disease: pathogenesis and clinical aspects. Dig Dis 26:149–155

    Article  PubMed  Google Scholar 

  • Philpotts LE, Heiken JP, Westcott MA, Gore RM (1994) Colitis: use of CT findings in differential diagnosis. Radiology 190:445–449

    PubMed  CAS  Google Scholar 

  • Ribeiro MB, Greenstein AJ, Yamazaki Y, Aufses AH Jr (1991) Intra-abdominal abscess in regional enteritis. Ann Surg 213:32–36

    Article  PubMed  CAS  Google Scholar 

  • Ros PR, Buetow PC, Pantograg-Brown L, Forsmark CE, Sobin LH (1996) Pseudomembranous colitis. Radiology 198:1–9

    PubMed  CAS  Google Scholar 

  • Schindera ST, Nelson RC, DeLong DM, Jaffe TA, Merkle EM, Paulson EK, Thomas J (2007) Multi-detector row CT of the small bowel: peak enhancement temporal window—initial experience. Radiology 243:438–444

    Article  PubMed  Google Scholar 

  • Schlatter M, Snyder K, Freyer D (2002) Successful nonoperative management of typhlitis in pediatric oncology patients. J Pediatr Surg 37:1151–1155

    Article  PubMed  Google Scholar 

  • Shamberger RC, Weinstein HJ, Delorey MJ, Levey RH (1986) The medical and surgical management of typhlitis in children with acute nonlymphocytic (myelogenous) leukemia. Cancer 57:603–609

    Article  PubMed  CAS  Google Scholar 

  • Soyer P, Martin-Grivaud S, Boudiaf M, Malzy P, Duchat F, Hamzi L, Pocard M, Vahedi K, Rymer R (2008) Linear or bubbly: a pictorial review of CT features of intestinal pneumatosis in adults. J Radiol 89:1907–1920

    Article  PubMed  CAS  Google Scholar 

  • Talbot RW, Heppell J, Dozois RR, Beart RW Jr (1986) Vascular complications of inflammatory bowel disease. Mayo Clin Proc 61:140–145

    PubMed  CAS  Google Scholar 

  • Thoeni RF, Cello JP (2006) CT imaging of colitis. Radiology 240:623–638

    Article  PubMed  Google Scholar 

  • Wagner ML, Rosenberg HS, Fernbach DJ, Singleton EB (1970) Typhlitis: a complication of leukemia in childhood. AJR Am J Roentgenol 109:341–350

    CAS  Google Scholar 

  • Wall SD, Jones B (1992) Gastrointestinal tract in the immunocompromised host: opportunistic infections and other complications. Radiology 185:327–335

    PubMed  CAS  Google Scholar 

  • Wood BJ, Kumar PN, Cooper C, Silverman PM, Zeman RK (1995) Pneumatosis intestinalis in adults with AIDS: clinical significance and imaging findings. AJR Am J Roentgenol 165:1387–1390

    PubMed  CAS  Google Scholar 

  • Yamamoto K, Kiyohara T, Murayama Y et al (2005) Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn’s disease. Gut 54:789–796

    Article  PubMed  CAS  Google Scholar 

  • Yilmaz T, Sever A, Gur S, Killi RM, Elmas N (2002) CT findings of abdominal tuberculosis in 12 patients. Comput Med Imaging Graph 26:321–325

    Article  PubMed  Google Scholar 

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Correspondence to Philippe Soyer .

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© 2011 Springer-Verlag Berlin Heidelberg

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Soyer, P., Boudiaf, M., Guerrache, Y., Hoeffel, C., Dray, X., Taourel, P. (2011). Nonischemic Colitis. In: Taourel, P. (eds) CT of the Acute Abdomen. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2011_159

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  • DOI: https://doi.org/10.1007/174_2011_159

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-89231-1

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