Abstract
Magnetic resonance imaging is used in oncology in particular for tumor staging, planning of surgery and radiation therapy, and monitoring of tumor response and early detection of recurrence. For all applications high field MRI can be advantageous, because the spatial resolution of the MR images is increasing with field strength, and thus smaller lesions become detectable. Furthermore, functional imaging techniques benefit from the higher field strength, which are used as early indicators for therapy response or tumor recurrence before morphological changes are visible. Several technical limitations such as the increased specific absorption rates (SAR), the limited B1 homogeneity of the transmit coils or the increased image distortion due to susceptibility differences make high field MRI of tumors challenging. Nevertheless, high resolution morphological and functional images of brain tumors have been acquired showing the internal tumor structure, the presence of neo-angiogenic vessels, and the functional changes of the tumor tissue.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Atkinson IC, Thulborn KR (2010) Feasibility of mapping the tissue mass corrected bioscale of cerebral metabolic rate of oxygen consumption using 17-oxygen and 23-sodium MR imaging in a human brain at 9.4 T. Neuroimage. 51(2):723–733
Christoforidis GA, Grecula JC, Newton HB, Kangarlu A, Abduljalil AM, Schmalbrock P, Chakeres DW (2002) Visualization of microvascularity in glioblastoma multiforme with 8-T high-spatial-resolution MR imaging. AJNR Am J Neuroradiol 23(9):1553–1556
Conolly S, Nishimura DG, Macovski A, Glover G (1988) Variable-rate selective excitation. J Magn Reson 78:440–458
Gardener AG, Gowland PA, Francis ST (2009) Implementation of quantitative perfusion imaging using pulsed arterial spin labeling at ultra-high field. Magn Reson Med 61(4):874–882
Kang CK, Hong SM, Han JY, Kim KN, Kim SH, Kim YB, Cho ZH (2008) Evaluation of MR angiography at 7.0 Tesla MRI using birdcage radio frequency coils with end caps. Magn Reson Med 60(2):330–338
Kraff O, Theysohn JM, Maderwald S, Saylor C, Ladd SC, Ladd ME, Barkhausen J (2007) MRI of the knee at 7.0 Tesla. Rofo 179(12):1231–1235
Kraff O, Bitz AK, Kruszona S, Orzada S, Schaefer LC, Theysohn JM, Maderwald S, Ladd ME, Quick HH (2009) An eight-channel phased array RF coil for spine MR imaging at 7 T. Invest Radiol 44(11):734–740
Maderwald S, Ladd SC, Gizewski ER, Kraff O, Theysohn JM, Wicklow K, Moenninghoff C, Wanke I, Ladd ME, Quick HH (2008) To TOF or not to TOF: strategies for non-contrast-enhanced intracranial MRA at 7 T. MAGMA 21(1–2):159–167
Mönninghoff C, Maderwald S, Theysohn JM, Schütt P, Gauler T, Kraff O, Ladd ME, Ladd SC, Wanke I (2010) Imaging of brain metastases of bronchial carcinomas with 7 T MRI—initial results. Rofo 182(9):764–772
Ogawa S, Lee TM, Kay AR, Tank DW (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868–9872
Ouwerkerk R (2007) Sodium magnetic resonance imaging: from research to clinical use. J Am Coll Radiol 4(10):739–741
van der Zwaag W, Francis S, Head K, Peters A, Gowland P, Morris P, Bowtell R (2009) fMRI at 1.5, 3 and 7 T: characterising BOLD signal changes. Neuroimage 47(4):1425–1434
von Morze C, Xu D, Purcell DD, Hess CP, Mukherjee P, Saloner D, Kelley DA, Vigneron DB (2007) Intracranial time-of-flight MR angiography at 7T with comparison to 3T. J Magn Reson Imaging 26(4):900–904
Wright PJ, Mougin OE, Totman JJ, Peters AM, Brookes MJ, Coxon R, Morris PE, Clemence M, Francis ST, Bowtell RW, Gowland PA (2008) Water proton T1 measurements in brain tissue at 7, 3, and 1.5 T using IR-EPI, IR-TSE, and MPRAGE: results and optimization. MAGMA 21(1–2):121–130
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2012 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Bock, M., Delorme, S., Gerigk, L. (2012). Oncology. In: Hennig, J., Speck, O. (eds) High-Field MR Imaging. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2010_105
Download citation
DOI: https://doi.org/10.1007/174_2010_105
Published:
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-85087-8
Online ISBN: 978-3-540-85090-8
eBook Packages: MedicineMedicine (R0)