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Modern NMR Methodology pp 1–22Cite as

NMR Spectroscopy for Chemical Analysis at Low Magnetic Fields

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Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 335))

Abstract

This chapter addresses the limits of low-field NMR spectroscopy for chemical analysis and will answer the question of whether high-resolution NMR spectroscopy for chemical analysis of solutions can be achieved with magnetic fields much lower than 0.1 T without losing the chemical information which at high field is derived from the chemical shift and the indirect spin–spin or J-coupling. The focus is on two major issues. First, the thermal spin population differences given by the Boltzmann distribution are small at low field and so is the signal-to-noise-ratio when starting measurements from thermal equilibrium. Second, the possibility of identifying chemical groups is explored at low magnetic fields where the chemical shift can usually no longer be resolved.

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Abbreviations

ALTADENA:

Adiabatic longitudinal transport after dissociation engenders net alignment

DNP:

Dynamic nuclear polarization

PASADENA:

Parahydrogen and synthesis allow dramatically enhanced nuclear alignment

PHIP:

Para-hydrogen induced polarization

SABRE:

Signal amplification by reversible exchange

SEOP:

Spin exchange optical pumping

SPINOE:

Spin polarization induced nuclear Overhauser effect

SQUID:

Superconducting quantum interference device

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Author information

Authors and Affiliations

  1. Institute for Technical Chemistry and Macromolecular Chemistry, RWTH Aachen, 52056, Aachen, Germany

    Stefan Glöggler, Bernhard Blümich & Stephan Appelt

  2. II. Institute of Physics, RWTH Aachen University, 52056, Aachen, Germany

    Stefan Glöggler

  3. Central Institute for Electronics, Research Center Jülich, 52425, Jülich, Germany

    Stephan Appelt

Authors
  1. Stefan Glöggler
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  2. Bernhard Blümich
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  3. Stephan Appelt
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Corresponding author

Correspondence to Bernhard Blümich .

Editor information

Editors and Affiliations

  1. , ICS-6 / Strukturbiologie und Biophysik, Heinrich-Heine-Universität Düsseldorf/ F, Jülich, Jülich, 52425, Germany

    Henrike Heise

  2. , Division of Molecular Biosciences, Imperial College London, South Kensington, London, SW72AZ, United Kingdom

    Stephen Matthews

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Glöggler, S., Blümich, B., Appelt, S. (2011). NMR Spectroscopy for Chemical Analysis at Low Magnetic Fields. In: Heise, H., Matthews, S. (eds) Modern NMR Methodology. Topics in Current Chemistry, vol 335. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_2011_304

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