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Biotechnology in China II pp 43–71Cite as

Organic Chemicals from Bioprocesses in China

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Part of the book series: Advances in Biochemical Engineering / Biotechnology ((ABE,volume 122))

Abstract

Over the last 20 years, China has successfully established a modern biotechnology industry from almost nothing. Presently, China is a major producer of a vast array of products involving bioprocesses, for some China is even the world’s top producer. The ever-increasing list of products includes organic acids, amino acids, antibiotics, solvents, chiral chemicals, biopesticides, and biopolymers. Herein, the research and development of bioprocesses in China will be reviewed briefly. We will concentrate on three categories of products: small molecules produced via fermentation, biopolymers produced via fermentation and small chemicals produced by enzyme-catalyzed reactions. In comparison with the traditional chemical process, in which, nonrenewable mineral resources are generally used, products in the first and second categories noted above can use renewable bioresources as raw materials. The bioprocesses are generally energy saving and environmentally benign. For products developed via the third category, although the raw materials still need to be obtained from mineral resources, the biocatalysts are more effective with higher selectivity and productivity, and the bioprocesses occur under ambient temperature and pressure, therefore, these are “green processes.” Most of the products such as citric acid, xanthan and acrylamide etc., discussed in this paper have been in large-scale commercial production in China. Also introduced herein are three scientists, Prof. Shen Yinchu, Prof. Ouyang Pingkai and Prof. Chen Guoqiang, and six enterprises, Anhui Fengyuan Biochemical Co. Ltd., Shandong Hiland Biotechnology Co. Ltd., Shandong Fufeng Fermentation Co. Ltd., Shandong Bausch & Lomb-Freda Pharmaceutical Co. Ltd., Zhejiang Hangzhou Xinfu Pharmaceutical Co. Ltd., and Changzhou Changmao Biochemical Engineering Co. Ltd.; they have all contributed a great deal to research and development in the commercialization of bioprocesses.

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Acknowledgments

Preparation of this manuscript was supported in part by the National Basic Research Program of China, 2007CB714304.

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Authors and Affiliations

  1. Department of Chemical Engineering and Biological Engineering, Zhejiang University (Yuquan Campus), Hangzhou, 310027, People’s Republic of China

    Jin Huang, Lei Huang, Jianping Lin, Zhinan Xu & Peilin Cen

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Correspondence to Peilin Cen .

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Editors and Affiliations

  1. A.A. Potter Engineering Center, Lab. Renewable Resources Engineering, Purdue University, West Lafayette, 47907, USA

    G. T. Tsao

  2. College of Life Science &, Pharmaceutical Engineering, Nanjing University of Technology, Xinmofan Road 5, Nanjing, 210009, China, People's Republic

    Pingkai Ouyang

  3. School of Biotechnology, Jiangnan University, Lihu Avenue 1800, Wuxi, 214122, China, People's Republic

    Jian Chen

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Huang, J., Huang, L., Lin, J., Xu, Z., Cen, P. (2010). Organic Chemicals from Bioprocesses in China. In: Tsao, G., Ouyang, P., Chen, J. (eds) Biotechnology in China II. Advances in Biochemical Engineering / Biotechnology, vol 122. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2010_75

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