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Biosystems Engineering II pp 139–162Cite as

Impact of Thermodynamic Principles in Systems Biology

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Part of the book series: Advances in Biochemical Engineering / Biotechnology ((ABE,volume 121))

Abstract

It is shown that properties of biological systems which are relevant for systems biology motivated mathematical modelling are strongly shaped by general thermodynamic principles such as osmotic limit, Gibbs energy dissipation, near equilibria and thermodynamic driving force. Each of these aspects will be demonstrated both theoretically and experimentally.

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Authors and Affiliations

  1. Department Biotechnology, Bioprocess technology, Delft University of Technology, Julianalaan 67, 2628 BC, Delft, The Netherlands

    J. J. Heijnen

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  1. J. J. Heijnen
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Correspondence to J. J. Heijnen .

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Editors and Affiliations

  1. Inst. Bioverfahrenstechnik, TU Braunschweig, Gaußstraße 17, Braunschweig, 38106, Germany

    Christoph Wittmann

  2. Inst. Bioverfahrenstechnik, TU Braunschweig, Gaußstraße 17, Braunschweig, 38106, Germany

    Rainer Krull

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Heijnen, J.J. (2010). Impact of Thermodynamic Principles in Systems Biology. In: Wittmann, C., Krull, R. (eds) Biosystems Engineering II. Advances in Biochemical Engineering / Biotechnology, vol 121. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2009_63

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