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Innate and T Cell-Mediated Immune Responses in Cryptosporidiosis

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Book cover The Pathogenic Enteric Protozoa: Giardia, Entamoeba, Cryptosporidium and Cyclospora

Part of the book series: World Class Parasites ((WCPA,volume 8))

Abstract

A variety of innate immune responses may help to control early parasite replication, initiate inflammation and generate signals for T cell activation. Ultimately, elimination of infection involves CD4+ T cells that are of the Th1 (cell-mediated immunity) phenotype, but there may be a protective role for lymphocytes of the Th2 type (antibody-dependent responses). Intraepithelial lymphocytes have increased activity as a result of infection and may be important in the anti-cryptosporidial immune response.

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Authors and Affiliations

  1. Department of Diagnostic Medicine/Pathogiology, Mosier Hall, Kansas State University, Manhattan, KS, 66506-5705

    Carol R. Wyatt

  2. Barts and the London School of Medicine and Dentistry, Department of Adult and Paediatric Gastroenterology, DDRC, Turner St, London, E1 2AD, UK

    Vincent McDonald

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  1. Carol R. Wyatt
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  2. Vincent McDonald
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Editors and Affiliations

  1. University of Arizona, Tucson, Arizona

    Charles R. Sterling  & Rodney D. Adam  & 

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Wyatt, C.R., McDonald, V. (2004). Innate and T Cell-Mediated Immune Responses in Cryptosporidiosis. In: Sterling, C.R., Adam, R.D. (eds) The Pathogenic Enteric Protozoa: Giardia, Entamoeba, Cryptosporidium and Cyclospora. World Class Parasites, vol 8. Springer, Boston, MA. https://doi.org/10.1007/1-4020-7878-1_7

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  • DOI: https://doi.org/10.1007/1-4020-7878-1_7

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