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An, C.L., Gigliotti, F., and Harmsen, A.G. (2003). Exposure of immunocompetent adult mice to Pneumocystis carinii f. sp. muris by cohousing: Growth of P. carinii f. sp. muris and host immune response. Infect. Immun. 71: 2065–2070.
Angus, C.W., Tu, A., Vogel, P., Qin, M., and Kovacs, J.A. (1996). Expression of variants of the major surface glycoprotein on Pneumocystis carinii. J. Exp. Med. 183: 1229–1234.
Burke, B.A. and Good, R.A. (1973). Pneumocystis carinii infection. Medicine 52: 23–52.
Burns, S.M., Read, J.A., Yap, P.L., and Brettle, R.P. (1990). Reduced concentrations of IgG antibodies to Pneumocystis carinii in HIV-infected patients during active Pneumocystis carinii infection and the possibility of passive immunisation. J. Infect. 20: 33–39.
Chatterton, J.M.W., Joss, A.W.L., Pennington, T.H., and Ho-Yen, D.O. (1999). Usefulness of rat-derived antigen in the serodiagnosis of Pneumocystis carinii infection. J. Med. Microbiol. 48: 681–687.
Garvy, B.A. and Harmsen, A.G. (1996). Susceptibility to Pneumocystis carinii infection: Host responses of neonatal mice from immune or naive mothers and of immune or naive adults. Infect. Immun. 64: 3987–3992.
Garvy, B.A., Wiley, J.A., Gigliotti, F., and Harmsen, A.H. (1997). Protection against Pneumocystis carinii pneumonia by antibodies generated from either T helper 1 or T helper 2 responses. Infect. Immun. 65: 5052–5056.
Gigliotti, F. (1992). Host species-specific antigenic variation of a mannosylated surface glycoprotein of Pneumocystis carinii. J. Infect. Dis. 165: 329–336.
Gigliotti, F. and Hughes, W.T. (1988). Passive immunoprophylaxis with specific monoclonal antibody confers partial protection against Pneumocystis carinii pneumonitis in animal models. J. Clin. Invest. 81: 1666–1668.
Gigliotti, F. and McCool, T. (1996). Glycoprotein A is the immunodominant antigen of Pneumocystis carinii in mice following immunization. Parasitol. Res. 82: 90–91.
Gigliotti, F., Garvy, B.A., and Harmsen, A.G. (1996). Antibody-mediated shift in the profile of glycoprotein A phenotypes observed in a mouse model of Pneumocystis carinii pneumonia. Infect. Immun. 64: 1892–1899.
Gigliotti, F., Garvy, B.A., Haidaris, C.G., and Harmsen, A.G. (1998a). Recognition of Pneumocystis carinii antigens by local antibody-secreting cells following resolution of P. carinii pneumonia in mice. J. Infect. Dis. 178: 235–242.
Gigliotti, F., Wiley, J.A., and Harmsen, A.G. (1998b). Immunization with Pneumocystis carinii gpA is immunogenic but not protective in a mouse model of P. carinii pneumonia. Infect. Immun. 66: 3179–3182.
Gigliotti, F., Haidaris, C.G., Wright, T.W., and Harmsen, A.G. (2002). Passive intranasal monoclonal antibody prophylaxis against murine Pneumocystis carinii pneumonia. Infect. Immun. 70: 1069–1074.
Gigliotti, F., Harmsen, A.G., and Wright, T.W. (2003). Characterization of transmission of Pneumocystis carinii f. sp. muris through immunocompetent BALB/c mice. Infect. Immun. 71: 3852–3856.
Hanano, R., Reifenberg, K., and Kaufmann, S.H.E. (1996). Naturally acquired Pneumocystis carinii pneumonia in gene disruption mutant mice: Roles of distinct T-cell populations in infection. Infect. Immun. 64: 3201–3209.
Harmsen, A.G. and Stankiewicz, M. (1990). Requirement for CD4+ cells in resistance to Pneumocystis carinii pneumonia in mice. J. Exp. Med. 172: 937–945.
Harmsen, A.G. and Stankiewicz, M. (1991). T cells are not sufficient for resistance to Pneumocystis carinii pneumonia in mice. J. Protozool. 38: 44S–45S.
Harmsen, A.G., Chen, W., and Gigliotti, F. (1995). Active immunity to Pneumocystis carinii reinfection in T-cell-depleted mice. Infect. Immun. 63: 2391–2395.
Jain, A., Atkinson, T.P., Lipsky, P.E., Slater, J.E., Nelson, D.L., and Strober, W. (1999). Defects of T-cell effector function and post-thymic maturation in X-linked hyper-IgM syndrome. J. Clin. Invest. 103: 1151–1158.
Jalil, A., Moja, P., Lambert, C., Perol, M., Cotte, L., Livrozet, J.M., Boibieux, A., Vergnon, J.M., Lucht, F., Tran, R., Contini, C., and Genin, C. (2000). Decreased production of local immunoglobulin A to Pneumocystis carinii in bronchoalveolar lavage fluid from human immunodeficiency virus-positive patients. Infect. Immun. 68: 1054–1060.
Laursen, A.L. and Anderson, P.L. (1998). Low levels of IgG antibodies against Pneumocystis carinii among HIV-infected patients. Scand. J. Infect. Dis. 30: 495–499.
Laursen, A.L., Jensen, B.N., and Andersen, P.L. (1994). Local antibodies against Pneumocystis carinii in bronchoalveolar lavage fluid. Eur. Respir. J. 7: 679–685.
Laursen, A.L., Obel, N., Holmskov, U., Jensenius, J.C., Aliouat, E.M., and Anderson, P.L. (2003). Activation of the respiratory burst by Pneumocystis carinii. Efficiency of different antibody isotypes, complement, lung surfactant protein D, and mannan-binding lectin. APMIS 111: 405–415.
Lee, L.H., Gigliotti, F., Wright, T.W., Simpson-Haidaris, P.J., Weinberg, G.A., and Haidaris, C.G. (2000). Molecular characterization of KEX1, a kexin-like protease in mouse Pneumocystis carinii. Gene 242: 141–150.
Lund, F.E., Schuer, K., Hollifield, M., Randall, T.D., and Garvy, B.A. (2003). Clearance of Pneumocystis carinii in mice is dependent on B cells but not on P. carinii-specific antibody. J. Immunol. 171: 1423–1430.
Lundgren, B., Lebech, M., Lind, K., Nielson, J.O., and Lundgren, J.D. (1993). Antibody response to a major human Pneumocystis carinii surface antigen in patients without evidence of immunosuppression and in patients with suspected atypical pneumonia. Eur. J. Microbiol. Infect. Dis. 12: 105–109.
Macy, J.D., Weir, E.C., Compton, S.R., Shlomchik, M.J., and Brownstein, D.G. (2000). Dual infection with Pneumocystis carinii and Pasturella pneumotropica in B cell-deficient mice: Diagnosis and therapy. Lab. Animal Sci. 50: 49–55.
Marcotte, H., Levesque, D., Delanay, K., Bourgeault, A., de la Durantaye, R., Brochu, S., and Lavoie, M.C. (1996). Pneumocystis carinii infection in transgenic B cell-deficient mice. J. Infect. Dis. 173: 1034–1037.
Meuwissen, J.H.E.T., Tauber, I., Leeuwenberg, A.D.E.M., Beckers, J.J.A., and Siebe, M. (1977). Parasitologic and serologic observations of infection with Pneumocystis in humans. J. Infect. Dis. 136: 43–49.
Pascale, J.M., Shaw, M.M., Durant, P.J., Amador, A.A., Bartlett, M.S., Smith, J.W., Gregorty, R.L., and McLaughlin, G.L. (1999). Intranasal immunization confers protection against murine Pneumocystis carinii lung infection. Infect. Immun. 67: 805–809.
Peglow, S.L., Smulian, A.G., Linke, M.J., Pogue, C.L., Nurre, S., Crisler, J., Phair, J., Gold, J.W., Armstrong, D., and Walzer, P.D. (1990). Serologic responses to Pneumocystis carinii antigens in health and disease. J. Infect. Dis. 161: 296–306.
Rao, C.P. and Gelfand, E.W. (1983). Pneumocystis carinii pneumonitis in patients with hypogammaglobulinemia and intact T cell immunity. J. Pediatr. 103: 410–412.
Roths, J.B. and Sidman, C.L. (1992). Both immunity and hyperresponsiveness to Pneumocystis carinii result from transfer of CD4+ but not CD8+ T cells into severe combined immunodeficiency mice. J. Clin. Invest. 90: 673–678.
Roths, J.B. and Sidman, C.L. (1993). Single and combined humoral and cell-mediated immunotherapy of Pneumocystis carinii pneumonia in immunodeficient SCID mice. Infect. Immun. 61: 1641–1649.
Saulsbury, F.T., Bernstein, M.T., and Winkelstein, J.A. (1979). Pneumocystis carinii pneumonia as the presenting infection in congenital hypogammaglobulinemia. J. Pediatr. 95: 559–561.
Smulian, A.G., Sullivan, D.W., Linke, M.J., Halsey, N.A., Quinn, T.C., MacPhail, A.P., Hernandez Avila, M.A., Hong, S.T., and Walzer, P.D. (1993a). Geographic variation in the humoral response to Pneumocystis carinii. J. Infect. Dis. 167: 1243–1247.
Smulian, A.G., Theus, S.A., Denko, N., Walzer, P.D., and Stringer, J.R. (1993b). A 55 kDa antigen of Pneumocystis carinii: Analysis of the cellular immune response and characterization of the gene. Mol. Microbiol. 7: 745–753.
Snydman, D.R., Werner, B.G., Heinze-Lacey, B., Berardi, V.P., Tilney, N.L., Kirkman, R.L., Milford, E.L., Cho, S.I., Bush, H.L., and Levey, A.S. (1987). Use of cytomegalovirus immune globulin to prevent cytomegalovirus disease in renal-transplant recipients. N. Engl. J. Med. 317: 1049–1054.
Soulez, B., Dei-Cas, E., Charet, P., Mougeot, G., Caillaux, M., and Camus, D. (1989). The young rabbit: A nonimmunosuppressed model for Pneumocystis carinii pneumonia. J. Infect. Dis. 160: 355–356.
Stringer, S.L., Garbe, T., Sunkin, S.M., and Stringer, J.R. (1993). Genes encoding antigenic surface glycoproteins in Pneumocystis carinii from humans. J. Eukaryot. Microbiol. 40: 821–826.
Stringer, J.R., Cushion, M.T., and Wakefield, A. (2001). New nomenclature for the genus Pneumocystis. J. Eukaryot. Microbiol. Suppl: 184S–189S.
Tanaka, S., Kaji, Y., Taniyama, H., Matsukawa, K., Ochiai, K., and Itakura, C. (1994). Pneumocystis carinii pneumonia in a thoroughbred foal. J. Vet. Med. Sci. 56: 135–137.
Theus, S.A., Sullivan, D.W., Walzer, P.D., and Smulian, A.G. (1994). Cellular responses to a 55-kilodalton recombinant Pneumocystis carinii antigen. Infect. Immun. 62: 3479–3484.
Vargas, S.L., Ponce, C.A., Hughes, W.T., Wakefield, A.E., Weitz, J.C., Donoso, S., Ulloa, A.V., Madrid, P., Gould, S., Latorre, J.J., Ávila, R., Benveniste, S., Gallor, M., Belletti, J., and López, R. (1999). Association of primary Pneumocystis carinii infection and sudden infant death syndrome. Clin. Infect. Dis. 29: 1489–1493.
Vargas, S.L., Hughes, W.T., Santolaya, M.E., Ulloa, A.V., Ponce, C.A., Cabrera, C.E., Cumsille, F., and Gigliotti, F. (2001). Search for primary infection by Pneumocystis carinii in a cohort of normal, healthy infants. Clin. Infect. Dis. 32: 855–861.
Wada, M., Sunkin, S.M., Stringer, J.R., and Nakamura, Y. (1995). Antigenic variation by positional control of major surface glycoprotein gene expression in Pneumocystis carinii. J. Infect. Dis. 171: 1563–1568.
Walzer, P.D. and Rutledge, M.E. (1981). Humoral immunity in experimental Pneumocystis carinii infection I. Serum and bronchial lavage fluid antibody responses in rats. J. Lab. Clin. Med. 97: 820–833.
Wiley, J.A. and Harmsen, A.G. (1995). CD40 ligand is required for resolution of Pneumocystis carinii pneumonia in mice. J. Immunol. 155: 3525–3529.
Zeitlin, L., Cone, R.A., and Whaley, K.J. (1999). Using monoclonal antibodies to prevent mucosal transmission of epidemic infectious diseases. Emerg. Infect. Dis. 5: 66.
Zheng, M., Shellito, J.E., Marrero, L., Zhong, Q., Julian, S., Ye, P., Wallace, V., Schwarzenberger, P., and Kolls, J.K. (2001). CD4+ T cell-independent vaccination against Pneumocystis carinii in mice. J. Clin. Invest. 108: 1469–1474.
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Garvy, B.A., Gigliotti, F. (2005). Antibody-Mediated Immunity to Pneumocystis in the Lungs. In: Fidel, P.L., Huffnagle, G.B. (eds) Fungal Immunology. Springer, Boston, MA. https://doi.org/10.1007/0-387-25445-5_14
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