Abstract
Mass spectrometry has now become a mainstream technique in biology research. We first give a brief account highlighting the most important developments in mass spectrometry that may be useful for the study of protein-protein interaction; next, we discuss some interesting issues that are starting to emerge as we learn more about protein complexes; finally, we discuss in some detail one example of using mass spectrometry to study protein- protein interaction in the area of human genome maintenance, and propose a new concept that we termed “network analysis proteomics” that aims to identify modular protein interaction networks.
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Wang, Y., Yazdi, P., Qin, J. (2005). The Use of Mass Spectrometry in Studying Protein-Protein Interaction. In: Waksman, G. (eds) Proteomics and Protein-Protein Interactions. Protein Reviews, vol 3. Springer, Boston, MA. https://doi.org/10.1007/0-387-24532-4_3
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DOI: https://doi.org/10.1007/0-387-24532-4_3
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