Skip to main content
SpringerLink
Log in

HIV Treatment Advances as Prevention

  • Chapter
Beyond Condoms

  • 124 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Barroso PF, Schecter M, Gupta P, Melo M, Vieira M, Murta F, Souza Y and L Harrison. Effect of antiretroviral therapy on HIV shedding in semen. Ann Intern Med. 2000; 133: 280–284.

    PubMed  CAS  Google Scholar 

  • Blanche S, Rouzioux C, Mandelbrot L, Delfraissy JF and Mayaux MJ. Zidovudine-lamivudine for prevention of mother to child HIV-1 transmission. 6th Annual Conference on Retroviruses and Opportunistic Infections, Chicago, 1999. Abstract no. 267.

    Google Scholar 

  • Blauvelt A. A role of skin dendritic cells in the initiation of human immunodeficiency virus infection. Am J Med 1997; 102:16–20.

    Article  PubMed  CAS  Google Scholar 

  • Blower SM, Gershengorn HB and Grant RM. A tale of two futures: HIV and antiretroviral therapy in San Francisco. Science, January 28, 2000, 287, 650–654.

    Article  PubMed  CAS  Google Scholar 

  • Boden D, Hurley A, Zhang L, Cao Y, Guo Y, Jones E, Tsay J, Ip J, Farthing C, Limoli K, Parkin N, Markowitz M. HIV-1 drug resistance in newly infected individuals. JAMA, 1999, 282(12), 1135–1141.

    Article  PubMed  CAS  Google Scholar 

  • Bozzette S, Berry S, Duan N, Frankel MR, Leibowitz AA, Lefkowitz D, Emmons CA, Senterfitt JW, Berk ML, Morton SC, Shapiro MF. The care of HIV-infected adults in the United States. N Engl J Med, 1998, 339, 1897–904

    Article  PubMed  CAS  Google Scholar 

  • Cardo DM, Culver DH, Ciesielski CA, Srivastava PU, Marcus R, Abiteboul D, Heptonstall J, Ippolito G, Lot F, McKibben PS, Bell DM. A case-control study of HIV seroconversion in health care workers after percutaneous exposure. N Engl J Med 1997; 337:1485–90.

    Article  PubMed  CAS  Google Scholar 

  • Centers for Disease Control and Prevention. Guidelines for national human immunodeficiency virus case surveillance, including monitoring for human immunodeficiency virus infection and acquired immunodeficiency syndrome. MMWR, 1999, 48 (No, RR-13)

    Google Scholar 

  • Centers for Disease Control and Prevention. Resurgent bacterial sexually transmitted disease among men who have sex with men-King County, Washington, 1997–1999. MMWR, September 10, 1999, 48 (35), 773–777.

    Google Scholar 

  • Centers for Disease Control and Prevention. Increases in unsafe sex and rectal gonorrhea among men who have sex with men—San Francisco, 1994–1997. MMWR 1999;48:45–8.

    Google Scholar 

  • Centers for Disease Control and Prevention. Public Health Service guidelines for the management of health-care worker exposures to HIV and recommendations for postexposure prophylaxis. MMWR, 1998, 47 (RR 7); 1–33

    Google Scholar 

  • Centers for Disease Control and Prevention. Management of possible sexual, injecting-druguse, or other nonoccupational exposure to HIV, including considerations related to antiretroviral therapy public health service statement. MMWR, 1998, 47 (RR17); 1–14

    Google Scholar 

  • Connor EM, Sperling RS, Gelber R, Kiselev P, Scott G, O’Sullivan MJ, VanDyke R, Bey M, Shearer W, Jacobson RL, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med, 1994, 331, 1173.

    Article  PubMed  CAS  Google Scholar 

  • DiClemente, Funkhouser E, Wingood G, Fawal H, Vermund S. Russian roulette: are persons being treated with protease inhibitors gambling with high risk sex? Int Conf AIDS, 1998, 12:211 (abstract no. 14143).

    Google Scholar 

  • Downs AM and De Vincenzi I for the European Study Group in Heterosexual Transmission of HIV. Probability of heterosexual transmission of HIV: relationship to the number of unprotected sexual contacts. J Acquir Immun Def Synd and Hum Retro 1996; 11:388–395.

    CAS  Google Scholar 

  • Evans B, Darbyshire J, and Cartledge J. Should preventive antiretroviral treatment be offered following sexual exposure to HIV? Not Yet! Sex Transm Infect, 1998, 74, 146.

    PubMed  CAS  Google Scholar 

  • Fideli U, Allen S, Musonda R, Meinzen-Derr J, Decker D, Li L, and Aldrovandi GM. Virologic Determinants of Heterosexual Transmission in Africa. 7th Annual Conference on Retroviruses and Opportunistic Infections, San Francisco, 2000. Abstract no. 194.

    Google Scholar 

  • Gerberding JL. Incidence and prevalence of human immunodeficiency virus, hepatitis B virus, hepatitis C virus, and cytomegalovirus among health care personnel at risk for blood exposure: final report from a longitudinal study. J Infect Dis 1994. 170:1410–7.

    PubMed  CAS  Google Scholar 

  • Gupta P, Mellors J, Kingsley L, Riddler, Mandaleshwar K, Schreiber S, Cronin M and C Rinaldo. High viral load in semen of human immunodeficiency virus type 1 infected men at all stages of disease and its reduction by therapy with protease and nonnucleoside reverse transcriptase inhibitors. J Virol. 1997 Aug;71(8):62715.

    Google Scholar 

  • Hart C, Lennox J, Pratt-Palmore M, Wright TC, Schinazi RF, Evans Strickfaden T, Bush TJ, Schnell C, Conley LJ, Clancy KA, Ellerbrock TV. Correlation of human immunodeficiency virus type 1 RNA levels in blood and the female genital tract. J Infect Dis, 1999, 179 (4), 871–882.

    Article  PubMed  CAS  Google Scholar 

  • Havlir DV, Marschner IC, Hirsch MS, Collier AC, Tebas P, Bassett RL, Ioannidis JP, Holohan MK, Leavitt R, Boone G, Richman DD. Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy. N Engl J Med, 1998, 339, 1261–1268

    Article  PubMed  CAS  Google Scholar 

  • Henderson DK, Fahey BJ, Willy M, Schmitt JM, Carey K, Koziol DE, Lane HC, Fedio J, Saah AJ. Risk for occupational transmission of human immunodeficiency virus type 1 (HIV-1) associated with clinical exposures: a prospective evaluation. Ann Intern Med 1990; 113:740–6.

    PubMed  CAS  Google Scholar 

  • Kaplan J, Hanson D, Dworkin M, Frederick T, Bertolli J, Lindegren ML, Holmberg S, Jones JL. Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy. Clin Infect Dis, 2000; 30,S5–14.

    Google Scholar 

  • Lehman JS, Hecht FM, Wortley P, Lansky A, Stevens M, Fleming P. Are at-risk populations less concerned about HIV infection in the HAART era? In: Program and Abstracts of the 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA; January 30–February 2, 2000. Abstract 198:112.

    Google Scholar 

  • Little SJ, Daar ES, D’Aquila RT, Keiser PH, Connick E, Whitcomb JM, Hellmann NS, Petropoulos CJ, Sutton L, Pitt JA, Rosenberg ES, Koup RA, Walker BD, Richman DD. Reduced antiretroviral drug susceptibility among patients with primary HIV infection. JAMA 1999, 282 (12), 1142–1149.

    Article  PubMed  CAS  Google Scholar 

  • Lurie P, Miller S, Hecht F, Chesney M, and Lo B. Postexposure prophylaxis after nonoccupational HIV exposure: Clinical, ethical, and policy considerations. JAMA, 1998; 280:1769–1773

    Article  PubMed  CAS  Google Scholar 

  • Marks G, Burris S, and Peterman T. Reducing sexual transmission of HIV from those who know they are infected: the need for personal and collective responsibility. AIDS, 1999, 13, 297–306.

    Article  PubMed  CAS  Google Scholar 

  • Martin N, Roland ME, Bamberger JD, Chesney MA, Waldo C, Unick J, Lay C, Katz MH, Coates TJ, and JO Kahn. Post-exposure prophylaxis after sexual or drug-use exposure to HIV: final results from the San Francisco post-exposure prevention (PEP) project. Presented at the 7th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA; January 30–February 2, 2000. Abstract 196.

    Google Scholar 

  • McNaghten AD, Hanson D, Jones J, Dworkin MS, Ward JW. Effects of antiretroviral therapy and opportunistic illness primary chemoprophylaxis on survival after AIDS diagnosis. AIDS, 1999, 13, 1687–1695. Morris A, Zorrilla C, Vajaranant M, Dobles A, Cu-Uvin S, Jones T, Harwell J, Carlan S, Allen D. A review of protease inhibitors (PI) Use in 89 pregnancies. 6th Annual Conference on Retroviruses and Opportunistic Infections, Chicago, 1999. Abstract no. 686.

    Article  PubMed  CAS  Google Scholar 

  • Murphy S, Miller L, Appleby R, Marks G and Mansergh G. Antiretroviral drugs and sexual behavior in gay and bisexual men: when optimism enhances risk Int Conf AIDS, 1998, 12:211 (abstract no. 14137).

    Google Scholar 

  • National Center for Health Statistics. Health, United States, 1999 with Health and Aging Chartbook. Hyattsville, Maryland: 1999.

    Google Scholar 

  • Otten RA, Smith DK, Adams DR, Pullium JK, Jackson E, Kim CN, Jaffe H, Janssen R, Butera S, Folks TM. Efficacy of postexposure prophylaxis after intravaginal exposure of pigtailed macaques to a humanderived retrovirus (human immunodeficiency virus type 2). J Virol. 2000 Oct;74(20):97715.

    Article  Google Scholar 

  • Palella F, Delaney M, Moorman A, Loveless MO, Fuhrer J, Satten GA, Aschman DJ, Holmberg SD. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N Engl J Med, 1998, 338, 853–860.

    Article  PubMed  Google Scholar 

  • Pialoux G, Raffi F, BrunVezinet F, Meiffredy V, Flandre P, Gastaut JA, Dellamonica P, Yeni P, Delfraissy JF, Aboulker JP. A randomized trial of three maintenance regimens given after three months of induction therapy with zidovudine, lamivudine, and indinavir in previously untreated HIV 1 infected patients. N Engl J Med, 1998, 339, 1269–1276

    Article  PubMed  CAS  Google Scholar 

  • Quinn TC, Wawer MJ, Sewankambo N, Serwadda D, Li C, Wabwire Mangen F, Meehan MO, Lutalo T, Gray RH. Viral load and heterosexual transmission of human immunodeficiency virus type 1. N Engl J Med 2000;342:921–9.

    Article  PubMed  CAS  Google Scholar 

  • Schwarcz-Kaplan S. Trends in HIV incidence among STD clients in the San Francisco Health Department-1989–98. Presented at National HIV Prevention Conference, 1999, August 29–September 1, Atlanta, Georgia.

    Google Scholar 

  • Shaffer N, Roongpisuthipong A, Siriwasin W, Chotpitayasunondh T, Chearskul S, Young NL, Parekh B, Mock PA, Bhadrakom C, Chinayon P, Kalish ML, Phillips SK, Granade TC, Subbarao S, Weniger BG, Mastro TD. Maternal viral load and perinatal HIV-1 subtype E transmission, Bangkok, Thailand. J Infect Dis, 1999, 179, 590–599.

    Article  PubMed  CAS  Google Scholar 

  • Shapiro M, Morton S, McCafrey D, Senterfitt J, Fleishman J, Perlman J, Athey L, Keesey J, Goldman D, Berry S, Bozzette S et al. Variations in the care of HIV-infected adults in the United States. Results from the HIV cost and services utilization study. JAMA, June 23/30, 1999, 281:24, 2305–2315.

    Article  PubMed  CAS  Google Scholar 

  • Tokars JI, Marcus R, Culver DH, Schable CA, McKibben PS, Bandea CI, Bell DM. Surveillance of HIV infection and zidovudine use among health care workers after occupational exposure to HIV-infected blood. Ann Intern Med 1993; 118:913–9.

    PubMed  CAS  Google Scholar 

  • UNAIDS/99.53E-WHO/CDS/CSR/EDC/99.9-WHO/FCH/HSI/99.6 AIDS epidemic update: December 1999.

    Google Scholar 

  • Wiebe ER; Comay SE; McGregor M; Ducceschi S. Offering HIV prophylaxis to people who have been sexually assaulted: 16 months’ experience in a sexual assault service. CMAJ 2000 Mar 7;162(5):6415

    Google Scholar 

  • Zhang H, Geethanjali D, Beumont M, Livornese L, Uitert B, Henning K and Pomerantz R. Human Immunodeficiency virus type 1 in the semen of men receiving highly active antiretroviral therapy. N Engl J Med. 1998, 339, 1803–1809.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of HIV/AIDS Prevention, National Center for HIV, STD and TB Prevention Centers for Disease Control and Prevention, Atlanta, Georgia

    Lynn Paxton & Robert Janssen

Authors
  1. Lynn Paxton
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Robert Janssen
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Centers for Disease Control and Prevention, Atlanta, Georgia

    Ann O’Leary

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Kluwer Academic Publishers

About this chapter

Cite this chapter

Paxton, L., Janssen, R. (2002). HIV Treatment Advances as Prevention. In: O’Leary, A. (eds) Beyond Condoms. Springer, Boston, MA. https://doi.org/10.1007/0-306-47518-9_5

Download citation

  • DOI: https://doi.org/10.1007/0-306-47518-9_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46731-8

  • Online ISBN: 978-0-306-47518-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation