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Molecular and Cellular Magnetic Resonance Contrast Agents

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Physics and Chemistry Basis of Biotechnology

Part of the book series: Focus on Biotechnology ((FOBI,volume 7))

Summary

Certain chemical structures have magnetic properties that enable faster proton relaxation, allowing their use as MR contrast agents or magnetopharmaceuticals when found biocompatible. Larger complexes such as macromolecular or particulate contrast agents have recently emerged as a distinct subgroup of magnetic materials, suitable for contrast enhancement of the blood pool and specific tissues. This chapter describes the latest advances in chemical engineering and molecular/cellularbiology,which are producing an entirely new class of (targeted) MR contrast agents that can be used for high-resolution imaging of biologic processes at the molecular and cellular level.

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Authors and Affiliations

  1. Laboratory of Diagnostic Radiology Research, Clinical Center, National Institutes of Health, Bethesda, MD, 20892

    J.W.M. Bulteand & L.H. Bryant Jr.

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  1. J.W.M. Bulteand
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  2. L.H. Bryant Jr.
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Editors and Affiliations

  1. Interdisciplinaire Research Center, Katholieke Universiteit Leuven, Kortrijk, Belgium

    Marcel De Cuyper

  2. National Institutes of Health, Bethesda, MD, USA

    Jeff W. M. Bulte

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© 2001 Kluwer Academic Publishers

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Bulteand, J., Bryant, L. (2001). Molecular and Cellular Magnetic Resonance Contrast Agents. In: De Cuyper, M., Bulte, J.W.M. (eds) Physics and Chemistry Basis of Biotechnology. Focus on Biotechnology, vol 7. Springer, Dordrecht. https://doi.org/10.1007/0-306-46891-3_8

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  • DOI: https://doi.org/10.1007/0-306-46891-3_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-0-7923-7091-8

  • Online ISBN: 978-0-306-46891-9

  • eBook Packages: Springer Book Archive

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