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Study and Description of Organic Reaction Mechanisms

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Advanced Organic Chemistry

Part of the book series: Advanced Organic Chemistry ((AOCA))

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4.13. Conclusion

To conclude this chapter, it is important to emphasize a logical point about the determination of reaction mechanisms. A proposed mechanism can never really be proven; rather, it is a case of alternative mechanisms being eliminated. Having in mind a mechanism that explains all the facts does not constitute proof that the mechanism is correct. That conclusion is possible only when all alternatives have been excluded. A key stage in a mechanistic investigation then is the enumeration of the various possible mechanisms and the design of experiments that distinguish between them. The principal basis for enumerating mechanistic possibilities is accumulated chemical experience with related systems and the inherent structural features of the system. A chemist approaching a mechanistic study must cast as broad as possible vision on the problem so as not to exclude possibilities.

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(2002). Study and Description of Organic Reaction Mechanisms. In: Advanced Organic Chemistry. Advanced Organic Chemistry. Springer, Boston, MA. https://doi.org/10.1007/0-306-46856-5_4

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  • DOI: https://doi.org/10.1007/0-306-46856-5_4

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