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References
Belehradek, J. B., Jr., Orlowski, S., Poddevin, B., Paoletti, C., and Mir, L. M., 1991, Electrochemistry of spontaneous mammary tumors in mice, Eur. J. Cancer 27:73–76.
Blank, I. H., and Scheuplein, R. J., 1969, Transport into and within the skin, Br. J. Dermatol. 81:4–10.
Bommannan, D. B., Tamada, J., Leung, L., and Potts, R. O., 1994, Effect of electroporation on transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH) i vitro, Pharm. Res. 11:1809–1814.
Burnette, R. R., and Marrero, D., 1986, Comparison between the iontophoretic and passive transport of thyrotropin releasing hormone across excised nude mouse skin, J. Pharm. Sci. 75:738–743.
Chang, D. C., and Reese, T. C., 1990, Changes in membrane structure induced by electroporation as revealed by rapid-freezing electron microscopy, Biophys. J. 58:1–12.
Chemomordik, L. V., and Chizmadzhev, Y. A., 1989, in: Electroporation and Electrofusion in Cell Biology (E. Neumann, A. E. Sowers, and C. A. Jordan, eds.), Plenum Press, New York, pp. 83–95
Chemomordik, L. V., Sukharev, S. I., Abidor, I. G., and Chizmadzhev, Y. A., 1983, Breakdown of lipid bilayer membranes in an electric field, Biochim. Biophys. Acta 736:203–213.
Chemomordik, L. V., Sukharev, S. I., Popov, S. V., Pastushenko, V. F., Sokiro, A. G., Abidor, I. G., and Chizmadzhev, Y. A., 1987, The electrical breakdown of cell and lipid membranes: The similarity of phenomenologies, Biochim. Biophys. Acta 902:360–373.
Chien, Y. W., Siddiqui, O., Shi, W.-M., Lelawongs, P., and Liu, J.-C., 1989, Direct current iontophoretic transdermal delivery of peptide and protein drugs, J. Pharm. Sci. 78:376–383.
Chizmadzhev, Y. A., Zarnytsin, V. G., Weaver, J. C., and Potts, R. 0. 1995, Mechanism of electroinduced ionic species transport through a multilamellar lipid system, Biophys. J., 68:749–765.
Elias, P. M., 1983, Epidermal lipids, barrier function, and desquamation, J. Invest. Dermatol. 80:44S–49S.
Elias, P. M., 1987, Plastic wrap revisited, Arch. Dermatol. 123:1405–1406.
Elias, P. M., 1991, Epidermal barrier function: Intercellular lamellar lipid structures, origin, composition and metabolism, J. Controlled Release 15:199–208.
Golden, G. M., Guzek, D. B., Kennedy, A. H., McKie, J. E., and Potts, R. O., 1987, Stratum corneum lipid phase transitions and water barrier properties, Biochemistry 26:2382–2388.
Green, P. G., Hinz, R. S., Cullander, C., Yamane, G. M., and Guy, R. H., 1991, Iontophoretic delivery of amino acids and amino acid derivatives across skin in vitro, Pharm. Res. 9:1113–1120.
Heit, M., Williams, P., Jayes, P., Chang, S., and Riviere, J., 1993, Transdermal iontophoretic peptide delivery: In vitro and in vivo studies with luteinizing hormone release hormone, J. Pharm. Sci. 82:240–243.
Heit, M. C., Monteiro-Riviere, N. A., Jayes, F. L., and Riviere, J. E., 1994, Transdermal iontophoretic delivery of luteinizing hormone releasing hormone (LHRH): Effect of repeated administration, Pharm. Res. 11:1000–1003.
Kinosita, K., Hibino, M., Itoh, H., Shigemori, M., Hirano, K., Kirino, Y., and Hayakawa, T., 1992, in: Guide to Electroporation and Electrofusion (D. C. Chang, B. M. Chassy, J. A. Saunders, and A. E. Sowers, eds.), Academic Press, New York, pp. 29–46.
Lelawongs, P., Liu, J.-C., Siddiqui, O., Chien, Y.-C., 1989, Transdermal iontophoretic delivery of arginine-vasopressin:Physicochemical considerations, Int. J. Pharm. 56:13–22.
Lu, M. F., Lee, D., and Rao, G. S., 1992, Percutaneous absorption enhancement of leuprolide, Pharm. Res. 9:1575–1579.
Meyer, B. R., Kreis, W., Eschbach, J., O’Mara, V., Rosen, S., and Sibalis, D., 1988, Successful transdermal administration of therapeutic doses of a polypeptide to normal human volunteers, Clin. Pharmacol. Ther. 44:607–612.
Meyer, R., Katzeff, H., Eschbach, J., Trimmer, J., Zacharias, S., Rosen, S., and Sibalis, D., 1989, Transdermal delivery of human insulin to albino rabbits using electrical current, Am. J. Med Sci. 297:321–325.
Miller, L. L., and Smith, G. A., 1989, Iontophoretic transport of acetate and carboxylate ions through hairless mouse skin. A cation exchange membrane model, Int. J. Pharm. 49:15–22.
Miller, L., Kolaskie, C., Smith, G., and Rivier, J., 1990, Transdermal iontophoresis of gonadotropin releasing hormone (LHRH) and two analogues, J. Pharm. Sci. 79:490–493.
Mir, L. M., Orlowski, S., Belehradek, J. B., Jr., and Paoletti, C., 1991, Electrochernotherapy potentiation of antitumor effect of bleomycin by local electric pulses, Eur. J. Cancer 27:68–72
Monteiro-Riviere, N. A., 1990, Altered epidermal morphology secondary to lidocaine iontophoresis: In vitro and in vivo studies in porcine skin, Fundam. Appl. Toxicol. 15:174–185.
Monteiro-Riviere, N. A., Inman, A. O., and Riviere, J. E., 1994, Identification of the pathway of transdermal iontophoretic drug delivery: Light and ultrastructural studies using mercuric chloride in pigs, Pharm. Res. 11:251–256.
Neumann, E., 1992, Membrane electroporation and direct gene transfer, Bioelectrochem. Bioenerg. 28:247–267.
Neumann, E., Sprafke, A., Boldt, E., and Wolf, H., 1992, in: Guide to Electroporation and Electrofusion (D. C. Chang, B. M. Chassy, J. A. Saunders, and A. E. Sowers, eds.), Academic Press, New York, pp. 77–90.
Oh, S. Y., Leung, L., Bommannan, D. B., Guy, R. H., and Potts, R. O., 1993, Effect of current, ionic strength and temperature on the electrical properties of skin, J. Controlled Release 27:115–125.
Potts, R. O., and Francoeur, M. L., 1990, Lipid biophysics of water loss through the skin, Proc. Natl. Acad. Sci. USA 87:3871–3873.
Potts, R. O., and Guy, R. H., 1992, Predicting skin permeability, Pharm. Res. 9:663–669.
Potts, R. O., Guy, R. H., and Francoeur, M. L., 1992, Routes of ionic permeability through mammalian skin, Solid State Ionics 53:165–169.
Prausnitz, M. R., Bose, V. G., Langer, R., and Weaver, J. C., 1993, Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery, Proc. Natl. Acad. Sci. USA 90:10504–10508.
Riviere, J. E., and Monteiro-Riviere, N. A., 1991, The isolated perfused porcine skin flap as an in vitro model for percutaneous toxicology, Crit. Rev. Toxicol. 21:329–344.
Riviere, J. E., Bowman, K. F., Monteiro-Riviere, N. A., Carver, M. P., and Dix, L. P., 1994. The isolated perfused porcine skin flat (IPPSF). I. A novel in vitro model for percutaneous absorption and cutaneous toxicology studies, Fundam. Appl. Toxicol. 7:444–453.
Riviere, J. E., Monteiro-Riviere, N. A., and Inman, A. O., 1992a, Determination of lidocaine concentrations in skin after transdermal iontophoresis: Effects of vasoactive drugs, Pharm. Res. 9:211–214.
Riviere, J. E. Williams, P. L., Hilman, R., and Mishky, L., 1992b, Quantitative prediction of transdermal iontophoretic delivery of arbutamine in humans using the in vitro isolated perfused porcine skin flap (IPPSF), J. Pharm. Sci. 81:504–507.
Riviere, J. E., Monteiro-Riviere, N. A., Rogers, R. A., Bommannan, D. B., Tamada, J. A., and Potts, R. O., 1995, Pulsatile transdermal delivery of LHRH using electroporation: Drug delivery and skin toxicology, J. Controlled Release 36:221–228.
Scheuplein, R. J., 1965, Mechanism of percutaneous adsorption. I. Routes of penetration and the influence of solubility, J. Invest. Dermatol. 45:334–346.
Scheuplein, R. J., 1978, Permeability of the skin: A review of major concepts, Curr. Probl. Dermatol. 7:172–186.
Siddiqui, O., Sun, Y., Liu, J.-C., and Chien, Y. W., 1987, Facilitated transdermal transport of insulin, J. Pharm. Sci. 76:341–345.
Singh, J., and Roberts, M., 1989, Transdermal delivery of drugs by iontophoresis: A review, Drug Des. Del. 41–12.
Srinivasan, V., Higuchi, W. I., Sims, S. M., Ghanem, A. H., and Behl, C. R., 1989, Transdermal iontophoretic drug delivery: Mechanistic analysis and application to polypeptide delivery, J. Pharm. Sci. 78:370–375.
Srinivasan, V., Su, M.-H., Higuchi, W. I., and Ekhl, C. R., 1990, Iontophoresis of polypeptides: Effect of ethanol pretreatment of human skin, J. Pharm. Sci. 79:588–591.
Titomirov, A. V., Sukharev, S., and Kistanova, E., 1991, In vivo electroporation and stable transformation of skin cells of newborn mice by plasmind DNA, Biochim. Biophys. Acta 1088:131–134.
Tsong, T. Y., 1990, On electroporation of cell membranes and some related phenomena, Bioelectrochem.Bioenerg. 24:271–295.
Wearley, L. L., and Chien, Y. W., 1990, Iontophoretic transdermal permeation of verapamil (III): Effect of binding and concentration gradient on reversibility of skin permeation rate, Int. J. Pharm. 59:87–94.
Yoshida, N. H., and Roberts, M. S., 1992, Structure-transport relationships in transdermal iontophoresis, Adv. Drug Delivery Rev. 9:239–264.
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Potts, R.0., Bommannan, D., Wong, 1., Tamada, J.A., Riviere, J.E., Monteiro-Riviere, N.A. (2002). Transdermal Peptide Delivery Using Electroporation. In: Sanders, L.M., Hendren, R.W. (eds) Protein Delivery. Pharmaceutical Biotechnology, vol 10. Springer, Boston, MA. https://doi.org/10.1007/0-306-46803-4_8
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