Chapter

New Polymer Materials

Volume 94 of the series Advances in Polymer Science pp 107-141

Date:

Phagocytosis of polymer microspheres by macrophages

  • Yasuhiko TabataAffiliated withResearch Center for Medical Polymers and Biomaterials, Kyoto University
  • , Yoshito IkadaAffiliated withResearch Center for Medical Polymers and Biomaterials, Kyoto University

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Abstract

This article reviews the phagocytosis of polymer microspheres by macrophages with respect to the size and the surface characteristics of the microspheres. Since few investigations have been carried out using well-characterized polymer microspheres, the authors have emphasized own experimental results. The findings provide useful information on the development of polymer microspheres as carriers for drug delivery systems.