Chapter

Telocytes

Volume 913 of the series Advances in Experimental Medicine and Biology pp 163-176

Date:

Telocytes in Exocrine Glands Stroma

  • Mihnea Ioan NicolescuAffiliated withHistology and Cytology Department, “Carol Davila” University of Medicine and Pharmacy“Victor Babeș” National Institute of Pathology Email author 

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Abstract

Stroma is viewed as the supportive framework of a predominant epithelial organ, comprising mostly of connective tissue, blood vessels and nerves. Since the discovery of telocytes one decade ago (Popescu and Faussone-Pellegrini J Cell Mol Med 2010;14(4):729–40), their presence was proven in several exocrine gland stromata, including major and minor salivary glands, mammary glands as well as exocrine pancreas.

Telocytes have been found in a close connection with acinar and ductal structures but also with their stromal neighbours – nerves, blood vessels or other connective elements, either cells or collagen fibres.

The approaches used to reveal the telocytes’ location were immunohistochemistry and electron microscopy.

Keywords

Mammary gland Pancreas Parotid Submandibular Telocytes