1987, pp 231-238

Proposal for a Phase Contrast X-ray Microscope

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Abstract

In x-ray microscopy experiments performed up to now the contrast is dominated by photoelectric absorption. The resulting radiation dose, though much less than in electron microscopy, limits fundamentally the resolution which can be obtained when investigating biological materials in the natural (intact wet and unstained) or living state, Sayre et al. (1977). Investigations to decouple resolution and radiation dose leads to a proposal for a phase contrast x-ray microscope. This work is based on experimental results on phase zone plates, Hilkenbach and Thieme (1986), and on the atomic scattering factors published by Henke (1981).