Japanese Encephalitis and West Nile Viruses

Volume 267 of the series Current Topics in Microbiology and Immunology pp 271-308

West Nile Virus in Livestock and Wildlife

  • R. G. McLeanAffiliated withNational Wildlife Health Center, United States Geological Survey
  • , S. R. UbicoAffiliated withNational Wildlife Health Center, United States Geological Survey
  • , D. BourneAffiliated withWildlife Information Network, The Royal Veterinary College
  • , N. KomarAffiliated withDivision of Vector-Borne Infectious Diseases, Arbovirus Diseases Branch, Centers for Disease Control and Prevention

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West Nile (WN) virus, the causative agent of West Nile fever, a dengue-like infection in humans, is one of the most widely distributed arthropod-borne viruses extending, until recently, from Africa, the Middle East, Europe, and western Asia. WN virus is a natural avian virus transmitted between birds primarily by ornithophilic mosquitoes, although isolations have been reported from mammals and amphibians, other mosquitoes and ticks. This virus has one of the broadest host and vector ranges and historically caused clinical disease in humans and equines only.