The scid Mouse Mutant

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Abstract

The scid mutation occurred in the C.B-17Icr (C.B-17) inbred strain, an immunoglobulin heavy chain (Igh) congenic partner strain of BALB/cAnlcr (BALB/c) . The C.B-17 strain was derived from the 13th backcross generation of the original C.B stock of M. Potter. C.B-17 mice are not known to differ from BALB/c mice except that a portion of their chromosome 12 comes from the C57BL/Ka strain and includes the C57BL/Ka Igh locus and other closely-linked genes.