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Miniature Differential Mobility Spectrometry (DMS) Advances towards Portable Autonomous Health Diagnostic Systems

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Wearable and Autonomous Biomedical Devices and Systems for Smart Environment

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 75))

Abstract

Many modern analytical instruments, such as mass spectrometry, have been developed to provide insight into the biochemical content of many different biological sample types. Typically these instruments are large bench-top machines that have very high sensitivity and specificity for the compounds they detect. However, these instruments are not mobile or autonomous, and they require highly trained personnel to operate. There have been many developments in the area of miniature chemical sensors that can maintain performance levels observed in large traditional bio-analytical instruments, but are low-power and potentially mobile and autonomous in function. Miniature differential mobility spectrometry (DMS) is a small instrument that can potentially be used in point-of-care diagnostic applications. This chapter will review the significant advances in this emerging research area, and provide insight as to how these systems could be further improved and adapted for use in autonomous health monitoring and sensing systems.

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Author information

Authors and Affiliations

  1. Mechanical and Aerospace Engineering,  

    Weixiang Zhao, Abhinav Bhushan & Cristina E. Davis

  2. Division of Pulmonary and Critical Care Medicine,  

    Michael Schivo & Nicholas J. Kenyon

  3. Clinical and Translational Science Center, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA

    Weixiang Zhao, Abhinav Bhushan, Michael Schivo, Nicholas J. Kenyon & Cristina E. Davis

Authors
  1. Weixiang Zhao
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  2. Abhinav Bhushan
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  3. Michael Schivo
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  4. Nicholas J. Kenyon
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  5. Cristina E. Davis
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Editor information

Editors and Affiliations

  1. Dipartimento d’Ingegneria dell’innovazione, University of Salento, Lecce, Italy

    Aimé Lay-Ekuakille

  2. School of Engineering and Advanced Technology (SEAT), Massey University (Turitea Campus), Palmerston North, New Zealand

    Subhas Chandra Mukhopadhyay

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Zhao, W., Bhushan, A., Schivo, M., Kenyon, N.J., Davis, C.E. (2010). Miniature Differential Mobility Spectrometry (DMS) Advances towards Portable Autonomous Health Diagnostic Systems. In: Lay-Ekuakille, A., Mukhopadhyay, S.C. (eds) Wearable and Autonomous Biomedical Devices and Systems for Smart Environment. Lecture Notes in Electrical Engineering, vol 75. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-15687-8_3

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  • DOI: https://doi.org/10.1007/978-3-642-15687-8_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-15686-1

  • Online ISBN: 978-3-642-15687-8

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