Abstract
A new method for sentinel lymph node detection was investigated by ex-vivo experiments in colorectal cancer. A dispersion of superparamagnetic iron oxide (SPIO) nanoparticles was injected in the resected tissue around the tumor. A magnetic probe with a 2nd order gradiometer configuration was used to localize the sentinel lymph node with accumulated SPIO nanoparticles. Additional analysis of SPIO content was performed on the resected lymph nodes. High-field MRI and conventional microscopy revealed the presence and distribution of SPIO inside the lymph nodes. Magnetometry confirmed SPIO content in lymph nodes and could give an estimate of the amount of SPIO uptake.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
ten Haken, B. et al. (2010). Magnetic Detection of the Sentinel Lymph Node in Ex Vivo Tissue with Colorectal Cancer. In: Supek, S., Sušac, A. (eds) 17th International Conference on Biomagnetism Advances in Biomagnetism – Biomag2010. IFMBE Proceedings, vol 28. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12197-5_107
Download citation
DOI: https://doi.org/10.1007/978-3-642-12197-5_107
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-12196-8
Online ISBN: 978-3-642-12197-5
eBook Packages: EngineeringEngineering (R0)