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Pathogenic Yeasts pp 167–190Cite as

Typing Species of Cryptococcus and Epidemiology of Cryptococcosis

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Part of the book series: The Yeast Handbook ((YEASTHDB))

Abstract

This article reviews the more common DNA-based molecular markers used to genotype species and strains of Cryptococcus. The current schemata for molecular epidemiological typing of C. neoformans and C. gattii are defined and summarized. Common methods of assessing the population genetics of the C. neoformans–C. gattii species complex are described and exemplified. In addition, the epidemiology, ecology and geographic distribution of Cryptococcus species and subpopulations are reviewed.

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Acknowledgement

This work was supported by a grant from the US Public Health Service, National Institutes of Health, R01 AI 25783.

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  1. Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, 27710, USA

    Thomas G. Mitchell & Anastasia P. Litvintseva

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  1. Thomas G. Mitchell
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Correspondence to Thomas G. Mitchell .

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  1. Old Medical School, Leeds General Infirmary, Leeds, LS1 3EX, United Kingdom

    Ruth Ashbee

  2. Div. Investigative Science, Imperial College London, South Kensington Campus, London , SW7 2AZ, United Kingdom

    Elaine M. Bignell

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Mitchell, T.G., Litvintseva, A.P. (2010). Typing Species of Cryptococcus and Epidemiology of Cryptococcosis. In: Ashbee, R., Bignell, E. (eds) Pathogenic Yeasts. The Yeast Handbook. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03150-2_8

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