Fertility Control

Volume 198 of the series Handbook of Experimental Pharmacology pp 29-35


Estrogen Signaling in the Regulation of Female Reproductive Functions

  • J. K. FindlayAffiliated withPrince Henry’s Institute of Medical Research Email author 
  • , S. H. LiewAffiliated withPrince Henry’s Institute of Medical Research
  • , E. R. SimpsonAffiliated withPrince Henry’s Institute of Medical Research
  • , K. S. KorachAffiliated withLaboratory of Reproductive and Developmental Toxicology, NIEHS/NIH

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Estrogens influence fertility and infertility in animals. This chapter reviews the use of estrogen as a contraceptive through the regulation of its production and action. It is concluded that the use of specific agonists and antagonists of estrogen action that avoid the global and unwanted side effects of estrogen offers new potential methods of contraception.


Aromatase Contraception Estrogen receptors Estrogens