An Exact Brownian Dynamics Method for Cell Simulation

  • Koichi Takahashi
Conference paper

DOI: 10.1007/978-3-540-88562-7_3

Part of the Lecture Notes in Computer Science book series (LNCS, volume 5307)
Cite this paper as:
Takahashi K. (2008) An Exact Brownian Dynamics Method for Cell Simulation. In: Heiner M., Uhrmacher A.M. (eds) Computational Methods in Systems Biology. CMSB 2008. Lecture Notes in Computer Science, vol 5307. Springer, Berlin, Heidelberg

Abstract

As we obtain better abilities to observe cellular biochemistry at the single cell / molecular levels, such as through fluorescent correlation spectroscopy and single particle tracking, evidences are accumulating that the cells may be taking advantage of intracellular spatial features to realize and optimize their functions. Computer simulation is a useful means to bridge the gap between the microscopic, physico-chemical picture of how macro-molecules diffuse and react, and the scales of time and space where biochemistry and physiology take place.

Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Koichi Takahashi
    • 1
  1. 1.The Molecular Sciences Institute, Berkeley, USA Computational Systems Biology Research Group, RIKEN, Yokohama, Japan Institute for Advanced BiosciencesKeio UniversityFujisawaJapan

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