A Survey of Computational Methods for Determining Haplotypes

  • Bjarni V. Halldórsson
  • Vineet Bafna
  • Nathan Edwards
  • Ross Lippert
  • Shibu Yooseph
  • Sorin Istrail
Conference paper

DOI: 10.1007/978-3-540-24719-7_3

Part of the Lecture Notes in Computer Science book series (LNCS, volume 2983)
Cite this paper as:
Halldórsson B.V., Bafna V., Edwards N., Lippert R., Yooseph S., Istrail S. (2004) A Survey of Computational Methods for Determining Haplotypes. In: Istrail S., Waterman M., Clark A. (eds) Computational Methods for SNPs and Haplotype Inference. RSNPsH 2002. Lecture Notes in Computer Science, vol 2983. Springer, Berlin, Heidelberg

Abstract

It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (SNPs) are the most common form of genomic variation. Haplotypes have been suggested as one means for reducing the complexity of studying SNPs. In this paper we review some of the computational approaches that have been taking for determining haplotypes and suggest new approaches.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2004

Authors and Affiliations

  • Bjarni V. Halldórsson
    • 1
  • Vineet Bafna
    • 1
  • Nathan Edwards
    • 1
  • Ross Lippert
    • 1
  • Shibu Yooseph
    • 1
  • Sorin Istrail
    • 1
  1. 1.Informatics Research, Celera Genomics/Applied BiosystemsRockville

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