Chapter

DNA Computing

Volume 2943 of the series Lecture Notes in Computer Science pp 190-196

Towards a Re-programmable DNA Computer

  • Danny van NoortAffiliated withDepartment of Ecology and Evolutionary Biology, Princeton University
  • , Laura F. LandweberAffiliated withDepartment of Ecology and Evolutionary Biology, Princeton University

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Abstract

Microreactors lend themselves to a relatively simple implementation of DNA computing. Not only is the design of the DNA library critical for the success of the system but also the architecture of the microfluidic structure. Microreactors can be configured as Boolean operators. This paper will show that biomolecular computing can be performed with elementary building blocks, analogous to electronic logic gates. These logical operations will be performed using negative selection. Furthermore, an alternative bead barrier is introduced which can render the computer re-programmable.