Chapter

Light-Responsive Nanostructured Systems for Applications in Nanomedicine

Volume 370 of the series Topics in Current Chemistry pp 169-202

Gold-Based Nanomaterials for Applications in Nanomedicine

  • Sumaira AshrafAffiliated withFachbereich Physik, Philipps Universität Marburg Email author 
  • , Beatriz PelazAffiliated withFachbereich Physik, Philipps Universität Marburg
  • , Pablo del PinoAffiliated withCIC biomaGUNE
  • , Mónica CarrilAffiliated withCIC biomaGUNEIkerbasque, Basque Foundation for Science
  • , Alberto EscuderoAffiliated withFachbereich Physik, Philipps Universität MarburgInstituto de Ciencia de Materiales de Sevilla, CSIC-University of Seville
  • , Wolfgang J. ParakAffiliated withFachbereich Physik, Philipps Universität MarburgCIC biomaGUNE
  • , Mahmoud G. SolimanAffiliated withFachbereich Physik, Philipps Universität Marburg
  • , Qian ZhangAffiliated withFachbereich Physik, Philipps Universität Marburg
  • , Carolina Carrillo-CarrionAffiliated withFachbereich Physik, Philipps Universität Marburg Email author 

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Abstract

In this review, an overview of the current state-of-the-art of gold-based nanomaterials (Au NPs) in medical applications is given. The unique properties of Au NPs, such as their tunable size, shape, and surface characteristics, optical properties, biocompatibility, low cytotoxicity, high stability, and multifunctionality potential, among others, make them highly attractive in many aspects of medicine. First, the preparation methods for various Au NPs including functionalization strategies for selective targeting are summarized. Second, recent progresses on their applications, ranging from the diagnostics to therapeutics are highlighted. Finally, the rapidly growing and promising field of gold-based theranostic nano-platforms is discussed. Considering the great body of existing information and the high speed of its renewal, we chose in this review to generalize the data that have been accumulated during the past few years for the most promising directions in the use of Au NPs in current medical research.

Keywords

Diagnostics Gold nanoparticles Nanomedicine Theranostics Therapeutics