Abstract
Quantification of neurotransmission Single-Photon Emission Computed Tomography (SPECT) studies of the dopaminergic system can be used to track, stage and facilitate early diagnosis of the disease. The aim of this study was to implement QuantiDOPA, a semi-automatic quantification software of application in clinical routine to reconstruct and quantify neurotransmission SPECT studies using radioligands which bind the dopamine transporter (DAT). To this end, a workflow oriented framework for the biomedical imaging (GIMIAS) was employed. QuantiDOPA allows the user to perform a semiautomatic quantification of striatal uptake by following three stages: reconstruction, normalization and quantification. QuantiDOPA is a useful tool for semi-automatic quantification inDAT SPECT imaging and it has revealed simple and flexible.
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© 2014 Springer International Publishing Switzerland
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Niñerola, A. et al. (2014). QuantiDOPA: A Quantification Software for Dopaminergic Neurotransmission SPECT. In: Roa Romero, L. (eds) XIII Mediterranean Conference on Medical and Biological Engineering and Computing 2013. IFMBE Proceedings, vol 41. Springer, Cham. https://doi.org/10.1007/978-3-319-00846-2_110
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DOI: https://doi.org/10.1007/978-3-319-00846-2_110
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-00845-5
Online ISBN: 978-3-319-00846-2
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