Chapter

Neurocutaneous Disorders Phakomatoses and Hamartoneoplastic Syndromes

pp 407-426

Silver Hair Syndromes: Chediak-Higashi Syndrome (CHS) and Griscelli Syndromes (GS)

  • Marimar Saez-De-OcarizAffiliated withDepartment of Dermatology, National Institute of Paediatrics
  • , Luz Orozco-CovarrubiasAffiliated withDepartment of Dermatology, National Institute of Paediatrics
  • , Carola Duràn-McKinsterAffiliated withDepartment of Dermatology, National Institute of Paediatrics
  • , Ramòn Ruiz-MaldonadoAffiliated withDepartment of Dermatology, National Institute of Paediatrics

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Normal pigmentation is a complex biological process and in the human, at least 127 different genes have been identified (Bennett and Lamoreaux 2003). Colour loci are the genetic loci in which mutations can affect pigmentation of the hair, skin, and/or eyes.