New Perspectives in Magnesium Research

pp 117-126

Clinical forms of Magnesium Depletion by Photosensitization and Treatment with Scototherapy

  • Jean DurlachAffiliated withInternational Society for the Development of Research on Magnesium (SDRM), Université Pierre et Marie Curie

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The clinical forms of magnesium depletion due to dysregulation biorhythms may result from the association of a low magnesium intake with a dysregulated biorhythm: either hyperfunction or hypofunction of the biological clock. Their main biological marker is the production of melatonin.1 The biological dysfunction of the biological clock may be primary (e.g., impaired maturation of photoneuroendocrine system in clinical forms of sudden infant death due to magnesium depletion by hypofunction of the biological clock)2,3 or secondary to light hypersensitivity. The organism responds to the pathogenic effect of this hypersensitivity with a protective reactive photophobia whose mechanism is still unclear.1,4–6