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Molecular Diagnostics for Neurological Disorders

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Applications of Biotechnology in Neurology

Abstract

Molecular diagnosis can be defined as the clinical application of molecular technologies to elucidate, diagnose, and monitor human diseases. Molecular technologies incorporate the use of nucleic acids (DNA and RNA) as well as recombinant antibodies. Proteomic technologies are also applied to molecular diagnosis, justifying the term “proteodiagnostics.” More than 500 molecular diagnostic systems have been developed to date. This article describes the basic principles of these technologies and their application to the diagnosis of neurologic disorders. The College of American Pathologists has used the term “molecular pathology” for molecular diagnostics, and as an extension of this, the application for neurologic disorders can be considered as “molecular neuropathology.” Imaging technologies have been refined to the molecular level and the term “molecular brain imaging” is suggested.

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  1. Jain PharmaBiotech, Basel, Switzerland

    Kewal K. Jain MD, FRACS, FFPM

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  1. Kewal K. Jain MD, FRACS, FFPM
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Jain, K.K. (2013). Molecular Diagnostics for Neurological Disorders. In: Applications of Biotechnology in Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-272-8_5

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