Chapter

Purine and Pyrimidine Metabolism in Man IX

Volume 431 of the series Advances in Experimental Medicine and Biology pp 735-739

Expression and Properties of Recombinant P. Falciparum Hypoxanthine-Guanine Phosphoribosyltransferase

  • D. T. KeoughAffiliated withDepartment of Biochemistry, University of QueenslandDepartment of Medicine, University of Queensland
  • , A.-L. NgAffiliated withDepartment of Biochemistry, University of Queensland
  • , B. T. EmmersonAffiliated withDepartment of Medicine, University of Queensland
  • , J. de JerseyAffiliated withDepartment of Biochemistry, University of Queensland

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Abstract

Plasmodium falciparum is the most deadly of the Plasmodium species causing human malaria. Due to the development of drug resistant strains of P falciparum, there is a need for the development of new antimalarial drugs.