Chapter

Mechanisms of Lymphocyte Activation and Immune Regulation VII

Volume 452 of the series Advances in Experimental Medicine and Biology pp 103-110

The Role of Dendritic Cells in the Initiation of Host Resistance to Toxoplasma Gondii

  • Alan SherAffiliated withLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  • , Sara HienyAffiliated withLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  • , Hugues CharestAffiliated withLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  • , Tanya Scharton-KerstenAffiliated withLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  • , Carmen CollazoAffiliated withLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  • , Ronald N. GermainAffiliated withLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health
  • , Caetano Reis e SousaAffiliated withLaboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Intracellular bacteria and protozoa typically stimulate host responses dominated by Type 1 cytokine production and cell-mediated immune effector functions. While the probable role of these responses is to limit growth of the infecting pathogen, the basis of their preferential induction is poorly understood and poses a fundamental question in immunologic class selection(1).