The Role of Dendritic Cells in the Initiation of Host Resistance to Toxoplasma Gondii

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Intracellular bacteria and protozoa typically stimulate host responses dominated by Type 1 cytokine production and cell-mediated immune effector functions. While the probable role of these responses is to limit growth of the infecting pathogen, the basis of their preferential induction is poorly understood and poses a fundamental question in immunologic class selection(1).