Genetic Engineering Volume 14, 1992, pp 13-31

Complications of RNA Heterogeneity for the Engineering of Virus Vaccines and Antiviral Agents

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Abstract

The most abundant viruses infecting plants, animals and humans are the RNA viruses (riboviruses and retroviruses). These elemental life forms are hypervariable to a degree that is difficult to comprehend fully. The genetics of RNA viruses is a strange, unfamiliar, and often counterintuitive genetics.