Chapter

Oxygen Transport to Tissue XIII

Volume 316 of the series Advances in Experimental Medicine and Biology pp 143-153

Experimentally Measured Optical Pathlengths for the Adult Head, Calf and Forearm and the Head of the Newborn Infant as a Function of Inter Optode Spacing

  • P. van der ZeeAffiliated withDepartments of Medical Physics, University College London
  • , M. CopeAffiliated withDepartments of Medical Physics, University College London
  • , S. R. ArridgeAffiliated withDepartments of Medical Physics, University College London
  • , M. EssenpreisAffiliated withDepartments of Medical Physics, University College London
  • , L. A. PotterAffiliated withDepartments of Paediatrics, University College London
  • , A. D. EdwardsAffiliated withDepartments of Paediatrics, University College London
  • , J. S. WyattAffiliated withDepartments of Paediatrics, University College London
  • , D. C. McCormickAffiliated withDepartments of Paediatrics, University College London
  • , S. C. RothAffiliated withDepartments of Paediatrics, University College London
    • , E. O. R. ReynoldsAffiliated withDepartments of Paediatrics, University College London
    • , D. T. DelpyAffiliated withDepartments of Medical Physics, University College London

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Abstract

The technique of near infrared spectroscopy (NIRS) is being increasingly used in clinical measurements of blood and tissue oxygenation (Wyatt et al 1986, Edwards et al 1990). and there are now several commercially produced instruments undergoing clinical testing. Whilst early NIR measurements were solely of a qualitative nature (Brazy et al 1985, 1986, Fox et al 1985. Ferrari et al 1986), techniques have now been developed to quantitate some parameters such as cerebral blood flow (Edwards et al. 1988a), cerebral blood volume (Wyatt et al 1990a) and muscle oxygen consumption (Cheatle et al 1990).