Chapter

Pediatric Gender Assignment

Volume 511 of the series Advances in Experimental Medicine and Biology pp 1-14

SRY and the Genetics of Sex Determination

  • Brian K. JordanAffiliated withDepartment of Human Genetics, UCLA School of Medicine
  • , Eric VilainAffiliated withDepartment of Human Genetics, UCLA School of Medicine

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Abstract

Many consider the distinction between the two sexes, male and female, to be absolute. Genetic studies of the mechanisms of sexual development have shown the complexity of sex determination and have started to unveil, at the molecular level, how a number of individuals can develop as intersex.