Hamlet — A Complex from Human Milk that Induces Apoptosis in Tumor Cells but Spares Healthy Cells

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Abstract

Breast-feeding has been proposed to protect both mother and child against cancer. The overall incidence of childhood cancer is reduced in breast-fed compared to bottle-fed individuals and decreases with the length of breast-feeding. Davis et al. compared 201 children diagnosed with cancer at an age of 1.5–15 years to 181 matched healthy controls, and found a crude odds ratio of 1.75 favoring infants breast-fed longer that 6 months.1 The epidemiological association was especially strong for lymphomas (crude odds ratio 5.62). This association has been verified in several other studies (reviewed in).2