Chapter

Retinal Degenerative Diseases

Volume 723 of the series Advances in Experimental Medicine and Biology pp 451-458

Date:

Imaging the Photoreceptor Mosaic with Adaptive Optics: Beyond Counting Cones

  • Pooja GodaraAffiliated withDepartment of Ophthalmology, Medical College of Wisconsin
  • , Melissa Wagner-SchumanAffiliated withDepartment of Ophthalmology, Medical College of WisconsinDepartments of Ophthalmology and Biophysics, Medical College of Wisconsin
  • , Jungtae RhaAffiliated withDepartment of Ophthalmology, Medical College of Wisconsin
  • , Thomas B. ConnorJr.Affiliated withDepartment of Ophthalmology, Medical College of Wisconsin
  • , Kimberly E. StepienAffiliated withDepartment of Ophthalmology, Medical College of Wisconsin
  • , Joseph CarrollAffiliated withDepartment of Ophthalmology, Medical College of WisconsinDepartments of Ophthalmology and Biophysics, Medical College of WisconsinDepartments of Ophthalmology and Biophysics, and Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin Email author 

Abstract

Recent years have seen an explosion in the development of novel ophthalmic imaging devices, delivering noninvasive views of the living retina. Adaptive optics (AO) imaging systems enable resolution of individual cells in the living retina. Analysis of these images has been limited to measures of cone density and regularity. Here, we introduce a small case series where the information in the high-resolution image extends beyond these standard metrics. These images should serve as the basis for evolving discussion as to how best to interpret AO retinal images.

Keywords

Adaptive optics Cone degeneration Photoreceptor RPE Retinal imaging