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The Reticuloendothelial System pp 339–353Cite as

Temperature Regulation and Fever

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Abstract

Body temperature is normally maintained over a narrow range by both behavioral and physiological means. Nonfebrile hyperthermia may occur, however, when heat-dissipating mechanisms are inadequate or fail (e.g., during heat stroke or malignant hyperthermia). Fever, on the other hand, represents a hyperthermic state in which body temperature is precisely controlled and homeostatic mechanisms not abandoned. During fever there is thought to be an upward resetting of the hypothalamic temperature set-point. This event leads to the activation of behavioral (e.g., putting on more clothing) and physiological (e.g., shivering) mechanisms which cause body temperature to rise to the new level (Cooper et al., 1964; MacPherson, 1959; Fox and MacPherson, 1954).

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Authors and Affiliations

  1. Department of Biology, Tufts University, Medford, Massachusetts, 02155, USA

    Harry A. Bernheim

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  1. Harry A. Bernheim
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Editors and Affiliations

  1. University of South Florida, Tampa, Florida, USA

    Herman Friedman

  2. Medical College of Virginia, Richmond, Virginia, USA

    Mario Escobar

  3. Medical College of Georgia, Augusta, Georgia, USA

    Sherwood M. Reichard

  4. Loyola University Medical Center, Maywood, Illinois, USA

    James P. Filkins

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© 1985 Plenum Press, New York

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Bernheim, H.A. (1985). Temperature Regulation and Fever. In: Friedman, H., Escobar, M., Reichard, S.M., Filkins, J.P. (eds) The Reticuloendothelial System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2353-2_14

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  • DOI: https://doi.org/10.1007/978-1-4613-2353-2_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9441-2

  • Online ISBN: 978-1-4613-2353-2

  • eBook Packages: Springer Book Archive

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