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Early Nutrition Programming and Health Outcomes in Later Life

Volume 646 of the series Advances in Experimental Medicine and Biology pp 95-104

Nutrient–Gene Interactions in Early Life Programming: Leptin in Breast Milk Prevents Obesity Later on in Life

  • Andreu PalouAffiliated withLaboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of the Balearic Islands (UIB) and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN) Email author 
  • , Juana SánchezAffiliated withLaboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of the Balearic Islands (UIB) and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN)
  • , Catalina PicóAffiliated withLaboratory of Molecular Biology, Nutrition and Biotechnology (Nutrigenomics), University of the Balearic Islands (UIB) and CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN)

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Breast milk is practically the only food eaten during the first months of life in fully breastfed infants and it is assumed to match the nutritional needs during these first months of postnatal life. Breastfeeding compared with infant formula feeding confers protection against several metabolic and physiological changes later on in life and, particularly, against obesity and related medical complications. Recent data from our laboratory, identifying leptin as the first specific compound responsible for these beneficial effects, are reviewed and discussed.

Keywords

Breastfeeding obesity leptin