Chapter

Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes

Volume 1 of the series Carbon Materials: Chemistry and Physics pp 181-221

Biomolecules Functionalized Carbon Nanotubes and Their Applications

  • Daxiang CuiAffiliated withDepartment of Bio-Nano Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key laboratory for thin film and microfabrication of Ministry of Education, Institute of Micro and Nano Science and Technology, Shanghai Jiaotong University

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Abstract

In recent years, functionalization of carbon nanotubes (CNTs) with biomolecules such as nucleotide acids, proteins, and artificial polymers have emerged as a new exciting field. Theoretical and experimental studies of structure and function of bio-inspired CNT composites have made great advances. The importance of nucleic acids, proteins, and synthesized polymers to the fundamental developments in CNT-based bio-nano-composites or devices has been recognized. In particular, biomechanics, biochemistry, thermodynamics, electronic, optical and magnetic properties, and biocompatibility and toxicology of the bio-inspired CNT composites have become a new interdisciplinary frontier in life science and nanomaterial science. Bio-inspired CNT composites have been actively exploited potentials in applications such as gene/drug delivery system, tissue engineering scaffolds, hydrogen storage, molecular imaging, biocatalyst systems, biosensors, and antifouling films. Here we review the main advances in this field over the past few years, explore their application prospects, and discuss the issues, approaches, and challenges, with the aim of improving and developing CNT-based bio-nanotechnology.

Keywords

Carbon nanotubes biomolecules nanocomposites functionalization applications