Sunlight, UV-Radiation, Vitamin D and Skin Cancer: How Much Sunlight Do We Need?
- Michael F. HolickAffiliated withDepartment of Medicine, Section of Endocrinology, Nutrition and Diabetes Vitamin D, Skin and Bone Research Laboratory, Boston University Medical Center
Vitamin D is the sunshine vitamin for good reason. During exposure to sunlight, the ultraviolet B photons enter the skin and photolyze 7-dehydrocholesterol to previtamin D3 which in turn is isomerized by the body’s temperature to vitamin D3. Most humans have depended on sun for their vitamin D requirement. Skin pigment, sunscreen use, aging, time of day, season and latitude dramatically affect previtamin D3 synthesis. Vitamin D deficiency was thought to have been conquered, but it is now recognized that more than 50% of the worlds population is at risk for vitamin D deficiency. This deficiency is in part due to the inadequate fortification of foods with vitamin D and the misconception that a healthy diet contains an adequate amount of vitamin D. Vitamin D deficiency causes growth retardation and rickets in children and will precipitate and exacerbate osteopenia, osteoporosis and increase risk of fracture in adults. The vitamin D deficiency has been associated pandemic with other serious consequences including increased risk of common cancers, autoimmune diseases, infectious diseases and cardiovascular disease. There needs to be a renewed appreciation of the beneficial effect of moderate sunlight for providing all humans with their vitamin D requirement for health.
- Sunlight, UV-Radiation, Vitamin D and Skin Cancer: How Much Sunlight Do We Need?
- Book Title
- Sunlight, Vitamin D and Skin Cancer
- pp 1-15
- Print ISBN
- Online ISBN
- Series Title
- Advances in Experimental Medicine and Biology
- Series Volume
- Series ISSN
- Springer New York
- Copyright Holder
- Landes Bioscience and Springer Science+Business Media
- Additional Links
- Industry Sectors
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- Jörg Reichrath (6)
- Editor Affiliations
- 6. Clinic for Dermatology, Venerology and Allergology, The Saarland University Hospital
- Author Affiliations
- 7. Department of Medicine, Section of Endocrinology, Nutrition and Diabetes Vitamin D, Skin and Bone Research Laboratory, Boston University Medical Center, 715 Albany Street, M-1013, Boston, MA, 02118, USA
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