Chapter

The Molecular Targets and Therapeutic Uses of Curcumin in Health and Disease

Volume 595 of the series ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY pp 245-268

CELL GROWTH REGULATION

  • Devarajan Karunagaran
  • , Jeena Joseph
  • , Thankayyan R. Santhosh Kumar

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Abstract

Curcumin, the active ingredient of turmeric (Curcuma longa) used in culinary and medical practices in Asia, has immense potential for being used in cancer chemotherapy because of its control over the cell growth regulatory mechanisms. The present chapter throws light on the role of curcumin in modulating the various phases of the cell cycle and its apoptosis-inducing effects. This is followed by a discussion on the implications of these effects of curcumin for its use as a chemotherapeutic agent in cancer.