2006, pp 1-6

Historical Background and Book Aim

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As early as 1976, in the preface to the first edition of his popular monograph on the physiology of the heart, Arnold M. Katz pointed out:

“...Although it remains fashionable to consider the heart as a muscular pump, this organ is much more than a hollow viscus that provides mechanical energy to propel blood through the vasculature. It is an intricate biological machine that contains, within each cell, a complex of control and effector mechanisms...” [1].