Cholera Outbreaks

Volume 379 of the series Current Topics in Microbiology and Immunology pp 195-209


Modeling Cholera Outbreaks

  • Dennis L. ChaoAffiliated withCenter for Statistics and Quantitative Infectious Diseases, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center Email author 
  • , Ira M. LonginiJr.Affiliated withDepartment of Biostatistics, Colleges of Public Health and Health Professions, and Medicine, and Emerging Pathogens Institute, University of Florida
  • , J. Glenn MorrisJr.Affiliated with Emerging Pathogens Institute, University of Florida

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Mathematical modeling can be a valuable tool for studying infectious disease outbreak dynamics and simulating the effects of possible interventions. Here, we describe approaches to modeling cholera outbreaks and how models have been applied to explore intervention strategies, particularly in Haiti. Mathematical models can play an important role in formulating and evaluating complex cholera outbreak response options. Major challenges to cholera modeling are insufficient data for calibrating models and the need to tailor models for different outbreak scenarios.