Abstract
From the time of the Hong Kong pandemic of 1968–1969, vaccines against influenza are trivalent, containing two subtypes of influenza type A: A/H1N1/ and A/H3N2/, and influenza type B. In 1980, circulation of the new Yamagata and Victoria lineages of influenza B virus was noted. Since both lineages have continued to circulate, the second lineage of influenza B was included into the trivalent vaccine as of the 2013/2014 epidemic season. In Poland, co-circulation of influenza type A and B has been registered over many seasons, although type A has predominated. According to the ACIP recommendations, quadrivalent vaccines against influenza are administered in some continents due to circulation of the B-Yamagata and B-Victoria lineages. Currently, only trivalent vaccines against influenza are available in Poland. The aim of the present research was to determine which of the two influenza type B lineages, or possibly both, would be isolated in Poland. The study was conducted with the use of RT-PCR. Generally, in the 2014/2015 epidemic season in Poland, circulation of type B virus was confirmed in 34 % of influenza cases. A total of 89 specimens of influenza B were tested, including co-infections of influenza B with influenza A subtypes: A/H1N1/pdm09 and A/H3N2/. The findings were that only lineage B-Yamagata circulates in the Polish population. Therefore, vaccines available on the Polish market do not require the introduction of a fourth component.
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Acknowledgements
This study was funded in parts by grants 2011/01/B/NZ7/06188 and NIPH-NIH’s subject 5/EM.1. We wish to acknowledge the team from the Worldwide Influenza Center of the Crick Institute in London, headed by John McCauley, for the analysis of Polish isolates within the Global Influenza Surveillance and Response System. We also thank the physicians and employees of VSESs participating in the SENTINEL program for their input into the influenza surveillance in Poland.
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The authors declare no conflicts of interest in relation to this article.
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Bednarska, K., Hallmann-Szelińska, E., Kondratiuk, K., Rabczenko, D., Brydak, L.B. (2015). Molecular Characteristics of Influenza Virus Type B Lineages Circulating in Poland. In: Pokorski, M. (eds) Respiratory Medicine and Science. Advances in Experimental Medicine and Biology(), vol 910. Springer, Cham. https://doi.org/10.1007/5584_2015_200
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DOI: https://doi.org/10.1007/5584_2015_200
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